Liu C, Chen X, Xu L
Research Department of Physiology, Beijing Institute of Oto-Rhino-Laryngology, China.
Acta Otolaryngol. 1992;112(2):215-20. doi: 10.1080/00016489.1992.11665407.
In this study, bilateral cochlear microphonics (CM) were evoked by tone burst simultaneously. A speaker was put in head-food axis 2 m from the mid-point of a given line connecting the bilateral external meatus. Five normal persons and 68 cases (34 cases of Meniere's disease, 27 cases of sudden hearing loss, and 7 cases of low-tone sensory hearing loss without vertigo) with unilateral sensory hearing loss and recruitment, in addition to 2 cases of bilateral Meniere's disease with recruitment were examined. CM shifted in normal and hearing loss ears and was absent in profound and totally deaf ears. When recruitment was present, CM at corresponding frequencies were enlarged and prolongated in 60 cases. Some of the enlarged and prolongated CM decayed slowly, others quickly. Meanwhile the CM of the opposite normal ear decreased obviously. The presence of enlarged and prolongated CM may indicate an increase of abnormal excitability of the hair cells caused by some pathological stimulations. This would cause excitability of the hair cells in the opposite cochlea to be inhibited by the effect of the efferent system. In such a condition, the patients complained that the stimulating sound was heard louder in the disordered ear than that in the opposite normal ear. CM was slightly enlarged during sleep.
在本研究中，通过同时给予短纯音诱发双侧耳蜗微音电位（CM）。将一个扬声器置于头部-食物轴上，距离连接双侧外耳道中点的给定直线中点2米处。对5名正常人和68例单侧感音神经性听力损失伴重振的患者（34例梅尼埃病、27例突发性听力损失和7例无眩晕的低音调感音神经性听力损失）以及2例双侧梅尼埃病伴重振的患者进行了检查。正常耳和听力损失耳的CM发生偏移，极重度聋耳和全聋耳未引出CM。当存在重振时，60例患者相应频率的CM增大且延长。一些增大延长的CM衰减缓慢，另一些则较快。与此同时，对侧正常耳的CM明显降低。CM增大延长可能表明某些病理刺激导致毛细胞异常兴奋性增加。这会使传出系统的作用抑制对侧耳蜗毛细胞的兴奋性。在这种情况下，患者主诉患耳听到的刺激声比另一侧正常耳更响。睡眠期间CM略有增大。
