Felix H, Johnsson L G, Gleeson M J, de Fraissinette A, Conen V
ENT Department, University Hospital, Zürich, Switzerland.
Acta Otolaryngol. 1992;112(2):284-7. doi: 10.1080/00016489.1992.11665419.
Fiber diameters were analyzed in the meatal segment of the cochlear nerve from 7 temporal bones obtained from 7 patients. Two patients had normal hearing for their age. Two had sustained noise exposure and one had presbyacusis of predominantly neural type. The cochleae displayed characteristic degeneration patterns. The other two manifested hearing loss of unspecified type. The fiber diameters ranged from 0.5 to 11 microns. The diameter distribution was unimodal in all seven nerves. The means of the diameters ranged from 4.2 to 5.5 microns. They were significantly different between patients with age-related normal hearing on the one hand and patients with noise induced hearing loss and neural presbyacusis on the other. The findings are discussed in relation to changes in nerve conduction speed and hearing loss; a possible correlation between the fiber diameter distribution and the tonotopical arrangement of the cochlea is suggested.
对取自7例患者的7块颞骨的蜗神经耳道段的纤维直径进行了分析。两名患者听力在其年龄阶段属正常。两名有持续噪声暴露史，一名主要为神经性老年性耳聋。耳蜗呈现出特征性的退变模式。另外两名表现为不明类型的听力损失。纤维直径范围为0.5至11微米。在所有七条神经中，直径分布均为单峰。直径平均值范围为4.2至5.5微米。一方面，年龄相关听力正常的患者与另一方面噪声性听力损失和神经性老年性耳聋的患者之间，这些平均值存在显著差异。结合神经传导速度变化和听力损失对这些发现进行了讨论；提示了纤维直径分布与耳蜗音调定位排列之间可能存在的相关性。
