Manjula S, Aroor A R, Raja A, Rao S N, Rao A
Department of Biochemistry, Kasturba Medical College, Manipal, India.
Acta Neurochir (Wien). 1992;115(3-4):103-5. doi: 10.1007/BF01406366.
Immunoglobulin level in the sera of 62 patients with intracranial space occupying lesions was assayed using the radial immunodiffusion method. Serum IgM levels showed a highly significant increase in all types of brain tumour when compared to controls. Serum IgG levels were also increased in benign as well as malignant cases. Serum IgA levels were high only in benign cases. Hence, increased serum Ig levels may be of prognostic value in these cases.
采用放射免疫扩散法检测了62例颅内占位性病变患者血清中的免疫球蛋白水平。与对照组相比,所有类型脑肿瘤患者的血清IgM水平均显著升高。良性和恶性病例的血清IgG水平也升高。血清IgA水平仅在良性病例中升高。因此,血清Ig水平升高在这些病例中可能具有预后价值。