Manjula S, Aroor A R, Raja A, Rao S N, Rao A
Department of Biochemistry, Kasturba Medical College, Manipal, Karnataka, India.
Acta Neurochir (Wien). 1995;133(3-4):164-8. doi: 10.1007/BF01420068.
The levels of circulating immune complexes (CIC) were assayed in the sera of 109 patients with intracranial space occupying lesions. The CIC levels were significantly increased in all the brain tumours. After treatment, the CIC levels were still significantly increased when compared to the controls but showed no change when compared to their respective pre-operative values. Further, no change was observed in the CIC levels between the malignant and benign tumour case. Moreover, in brain tumours, 90% of the CIC precipitate consisted of IgG. However, the CIC levels fail to prognosticate the process of the disease in these patients.
对109例颅内占位性病变患者的血清进行循环免疫复合物（CIC）水平检测。所有脑肿瘤患者的CIC水平均显著升高。治疗后，与对照组相比，CIC水平仍显著升高，但与各自术前值相比无变化。此外，恶性和良性肿瘤病例的CIC水平未观察到变化。而且，在脑肿瘤中，90%的CIC沉淀物由IgG组成。然而，CIC水平未能对这些患者的疾病进程进行预后判断。
