口腔癌、宫颈癌和乳腺癌患者的血清免疫球蛋白
Serum immunoglobulins in patients with carcinoma of the oral cavity, uterine cervix and breast.
作者信息
Vijayakumar T, Ankathil R, Remani P, Sasidharan V K, Vijayan K K, Vasudevan D M
出版信息
Cancer Immunol Immunother. 1986;22(1):76-9. doi: 10.1007/BF00205721.
Serum immunoglobulin levels (IgG, IgA, IgM, IgD and IgE) were estimated in 196 patients with carcinoma of the oral cavity, 172 patients with cervical cancer and 166 patients with breast cancer. The values were compared with those of 50 patients with benign lesions of the breast and cervix and 100 healthy adult controls. Only the serum IgE levels were found to be elevated in the benign group. Serum IgA, IgD and IgE levels were found to be elevated in all the three types of cancers and the levels were found to increase with clinical stage. In carcinoma of uterine cervix IgG levels were also found to be elevated. Immunoglobulins A and D returned to normal after clinical cure whereas IgE remained slightly elevated. IgD and IgE remained high in patients who had residual cancer.
对196例口腔癌患者、172例宫颈癌患者和166例乳腺癌患者的血清免疫球蛋白水平（IgG、IgA、IgM、IgD和IgE）进行了评估。将这些值与50例乳腺和宫颈良性病变患者以及100例健康成年对照者的值进行了比较。仅发现良性组血清IgE水平升高。在所有三种癌症类型中均发现血清IgA、IgD和IgE水平升高，且这些水平随临床分期增加。在子宫颈癌中也发现IgG水平升高。免疫球蛋白A和D在临床治愈后恢复正常，而IgE仍略有升高。在有残留癌的患者中，IgD和IgE仍保持高水平。
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