Gao Jing, Xiang Yong-bing, Xu Wang-hong, Shao Chang-xia, Ruan Zhi-xian, Cheng Jia-rong, Shu Xiao-ou, Gao Yu-tang
Shanghai Cancer Institute, Shanghai 200032, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2005 May;26(5):323-7.
To assess the effect of tea consumption on the risk of endometrial cancer.
In a population based case-control study conducted in urban Shanghai, face-to-face interviews were completed for 995 incidence cases aged 30 - 69 from January 1997 to December 2002 and 1087 controls that frequency-matched to cases on age. Unconditional logistic model was used for analysis.
An inverse association was observed in tea drinking and endometrial cancer risk. Compared to non-tea drinkers, regular tea drinkers had reduced risk of endometrial cancer (OR = 0.74; 95% CI: 0.54 - 1.01) in premenopausal women. Green tea had a protective effect on endometrial cancer among non-smoking or non-alcohol drinking women (OR = 0.77, P = 0.0199) and the ORs reduced with the increasing concentration of tea being served (P for trend = 0.0493). The multivariate ORs for drinking green tea < 7 times/week and >or= 7 times/week were 0.90 (95% CI: 0.53 - 1.54) and 0.76 (95% CI: 0.60 - 0.95) with the trend test of P = 0.0163.
Tea drinking, with green tea in particurlar, seemed to have weak but inverse association with endometrial cancer risk, but this effect of protection might only limit to premenopausal women.
评估饮茶对子宫内膜癌风险的影响。
在上海市区开展的一项基于人群的病例对照研究中，于1997年1月至2002年12月期间，对995例年龄在30 - 69岁的发病病例以及1087例年龄频率匹配的对照进行了面对面访谈。采用无条件逻辑模型进行分析。
观察到饮茶与子宫内膜癌风险之间存在负相关。与不饮茶者相比，绝经前女性中经常饮茶者患子宫内膜癌的风险降低（比值比[OR]=0.74；95%置信区间[CI]：0.54 - 1.01）。绿茶对不吸烟或不饮酒女性的子宫内膜癌具有保护作用（OR = 0.77，P = 0.0199），且随着饮茶量增加，OR值降低（趋势检验P = 0.0493）。每周饮用绿茶<7次和≥7次的多变量OR值分别为0.90（95% CI：0.53 - 1.54）和0.76（95% CI：0.60 - 0.95），趋势检验P = 0.0163。
饮茶，尤其是绿茶，似乎与子宫内膜癌风险存在微弱的负相关，但这种保护作用可能仅局限于绝经前女性。
