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面部咬伤:管理更新

Facial bite wounds: management update.

作者信息

Stefanopoulos P K, Tarantzopoulou A D

机构信息

Department of Oral and Maxillofacial Surgery, 401 General Army Hospital, Athens, Greece.

出版信息

Int J Oral Maxillofac Surg. 2005 Jul;34(5):464-72. doi: 10.1016/j.ijom.2005.04.001.

Abstract

Bite wounds are frequently located on the face; injuries inflicted by dogs are most common, especially in children. Bacteriology of infected dog and cat bite wounds includes Pasteurella multocida, Staphylococcus aureus, viridans streptococci, Capnocytophaga canimorsus, and oral anaerobes. Infected human bites yield a similar spectrum of bacteria except for Pasteurellae and C. canimorsus; instead human bites are frequently complicated by Eikenella corrodens. Antibiotic therapy against these bacteria is indicated both for infected bite wounds and fresh wounds considered at risk for infection. Amoxicillin-clavulanate (and other combinations of extended-spectrum penicillins with beta-lactamase inhibitors) and moxifloxacin offer the best in vitro coverage of the pathogenic flora. Initial wound management consisting in irrigation and debridement is at least equally important with antibiotics for prevention of infection. The need for prophylaxis against systemic infectious complications, particularly tetanus, should also be evaluated. Primary surgical repair is the treatment of choice for most clinically uninfected facial bite wounds, whereas delayed closure should be reserved for certain high risk or already infected wounds. Avulsive injuries with significant tissue loss represent the most difficult cases for definitive management and are also those most likely to require hospitalization.

摘要

咬伤伤口常位于面部;狗造成的伤害最为常见,尤其是在儿童中。感染的狗和猫咬伤伤口的细菌学包括多杀巴斯德菌、金黄色葡萄球菌、草绿色链球菌、犬咬二氧化碳嗜纤维菌和口腔厌氧菌。感染的人咬伤产生的细菌谱与之相似,但不包括巴斯德菌属和犬咬二氧化碳嗜纤维菌;相反,人咬伤常因腐蚀艾肯菌而复杂化。对于感染的咬伤伤口和被认为有感染风险的新鲜伤口,均需针对这些细菌进行抗生素治疗。阿莫西林-克拉维酸(以及其他广谱青霉素与β-内酰胺酶抑制剂的组合)和莫西沙星对病原菌具有最佳的体外覆盖范围。初始伤口处理包括冲洗和清创,与抗生素在预防感染方面至少同样重要。还应评估预防全身性感染并发症,尤其是破伤风的必要性。对于大多数临床上未感染的面部咬伤伤口,一期手术修复是首选治疗方法,而延迟缝合应保留用于某些高风险或已感染的伤口。伴有大量组织丢失的撕脱伤是确定性处理中最困难的病例,也是最有可能需要住院治疗的病例。

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