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左心室收缩功能障碍慢性心力衰竭患者样本中焦虑和抑郁的患病率及预测因素。

Prevalence and predictors of anxiety and depression in a sample of chronic heart failure patients with left ventricular systolic dysfunction.

作者信息

Haworth J E, Moniz-Cook E, Clark A L, Wang M, Waddington R, Cleland J G F

机构信息

Department of Clinical Psychology, Post Graduate Medical Institute, Hertford Building, University of Hull, Kingston-upon-Hull HU6 7RX, United Kingdom.

出版信息

Eur J Heart Fail. 2005 Aug;7(5):803-8. doi: 10.1016/j.ejheart.2005.03.001.

Abstract

OBJECTIVE

To determine the prevalence and predictors of anxiety and depression in patients with heart failure due to Left Ventricular Systolic Dysfunction (LVSD).

BACKGROUND

Psychological adjustment to Chronic Heart Failure (CHF) can be poor, with the prevalence of depression in out-patients ranging from 13% to 48%. The prevalence of anxiety disorders in this population is unknown and the factors that predict anxiety and depression are not well understood.

METHODS

100 out-patients from a community heart failure programme completed a clinical diagnostic interview--the Structured Clinical Interview (SCID-I), to evaluate anxiety and depression. Mean age was 67+/-11 years, 17% were women and 91% were NYHA Class II or III. Other standardised measures were of cognition, biomedical status, social support and previous physical and mental health history.

RESULTS

The prevalence rates of anxiety and depression (all subtypes) were 18.4% and 28.6%, respectively. Predictors of depression included a reported history of mental ill-health and NYHA class. Predictors of anxiety included a reported history of mental ill-health, co-morbid physical illness (diabetes and angina) and NYHA class. Severity of LVSD did not predict either anxiety or depression.

CONCLUSIONS

Both anxiety and depression are common in CHF patients. The data on the predictors of poor psychological adjustment might assist in targeting bio-psychosocial intervention for patients who are at most at risk of anxiety and depression, within community CHF disease management programmes.

摘要

目的

确定左心室收缩功能障碍(LVSD)所致心力衰竭患者焦虑和抑郁的患病率及预测因素。

背景

慢性心力衰竭(CHF)患者的心理调适可能较差,门诊患者中抑郁症的患病率在13%至48%之间。该人群中焦虑症的患病率尚不清楚,且预测焦虑和抑郁的因素也未得到充分了解。

方法

来自社区心力衰竭项目的100名门诊患者完成了一次临床诊断访谈——结构化临床访谈(SCID-I),以评估焦虑和抑郁情况。平均年龄为67±11岁,17%为女性,91%为纽约心脏协会(NYHA)心功能II级或III级。还采用了其他标准化测量方法来评估认知、生物医学状况、社会支持以及既往身心健康史。

结果

焦虑和抑郁(所有亚型)的患病率分别为18.4%和28.6%。抑郁的预测因素包括报告有精神疾病史和NYHA心功能分级。焦虑的预测因素包括报告有精神疾病史、合并躯体疾病(糖尿病和心绞痛)以及NYHA心功能分级。LVSD的严重程度并不能预测焦虑或抑郁。

结论

焦虑和抑郁在CHF患者中均很常见。关于心理调适不良预测因素的数据可能有助于在社区CHF疾病管理项目中,针对焦虑和抑郁风险最高的患者进行生物心理社会干预。

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