Hanssen Manon, Krabbendam Lydia, de Graaf Ron, Vollebergh Wilma, van Os Jim
Department of Psychiatry and Neuropsychology, Maastricht University, PO Box 616 (DRT 10), 6200 MD Maastricht, The Netherlands.
Br J Psychiatry Suppl. 2005 Aug;48:s55-8. doi: 10.1192/bjp.187.48.s55.
Contemporary cognitive psychological theories suggest that distress plays a mediating role in delusion formation.
To study the amplifying role of distress from early perceptual intrusions to delusion formation.
A general population sample of 7076 individuals was interviewed with the Composite International Diagnostic Interview (CIDI) in 1996 (baseline), 1997 (T1) and 1999 (T2). At T2, clinicians also scored the Brief Psychiatric Rating Scale (BPRS) item "unusual thought content". Analyses compared hallucinatory experiences with and without subjective distress at baseline for risk of delusion formation at follow-up.
Individuals experiencing hallucinations with distress, compared with those without distress had a fourfold increased risk of subsequent delusion formation.
This finding corroborates the hypothesis that distress associated with early perceptual intrusions serves as a catalyst in the development of delusions.
当代认知心理学理论表明，痛苦在妄想形成过程中起中介作用。
研究从早期感知侵扰到妄想形成过程中痛苦的放大作用。
1996年（基线）、1997年（T1）和1999年（T2），使用复合国际诊断访谈（CIDI）对7076名普通人群样本进行访谈。在T2时，临床医生还对简明精神病评定量表（BPRS）项目“异常思维内容”进行评分。分析比较了基线时伴有和不伴有主观痛苦的幻觉体验在随访时形成妄想的风险。
与无痛苦的幻觉体验者相比，有痛苦的幻觉体验者随后形成妄想的风险增加了四倍。
这一发现证实了以下假设，即与早期感知侵扰相关的痛苦是妄想发展的催化剂。
