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[腹腔镜胆囊切除术后医源性胆管损伤的外科治疗:长期结果分析。对1991年至2003年在坎帕尼亚地区接受手术的51例患者的回顾性临床研究]

[Surgical treatment of iatrogenic bile duct injuries following laparoscopic cholecystectomy: analysis of long-term results. Retrospective clinical study in 51 patients operated in the Campania region from 1991 to 2003].

作者信息

Conzo Giovanni, Amato Giuseppe, Angrisani Luigi, Bardi Ugo, Barone Giovanni, Belli Giulio, Brancaccio Umberto, Calise Fulvio, Caliendo Angelo, Celsi Salvatore, Corcione Francesco, Cuccurullo Diego, De Falco Giuseppe, Delrio Paolo, De Werra Carlo, De Sena Guido, Docimo Giovanni, Esposito Maria Grazia, Fantini Corrado, Giardiello Cristiano, Musella Mario, Molino Carlo, Muto Crescenzo, Pennetti Lucio, Puziello Alessandro, Porcelli Alberto, Rea Roberto, Rendano Franco, Palazzo Antonietta, Santangelo Michele, Santaniello Walter, Santini Luigi, Sperlongano Pasquale, Stanzione Francesco, Tartaglia Alberto, Tricarico Annunziato, Vincenti Rodolfo, Lorenzo Michele

机构信息

LAP Club, Gruppo collaborativo per lo studio della chirurgia videolaparoscopica, Città della Scienza, Napoli.

出版信息

Chir Ital. 2005 Jul-Aug;57(4):417-24.

Abstract

An higher incidence rate of iatrogenic bile duct injuries is reported in cholecystectomy performed with the laparoscopy than with the laparotomy approach. The aim of this study was to provide a multicentre report on surgical treatment and the outcome of biliary complications during and following laparoscopic cholecystectomy. A questionnaire was mailed to all surgeons with experience in laparoscopic cholecystectomy in the Campania region. Data were collected from January 1991 to December 2003. Each patient was requested to indicate age, gender, associated diseases, site and type of lesion, surgical experience, diagnosis, treatment and complications. Twenty-six surgeons answered the questionnaire. Fifty-one patients (36 F/15 M; mean age: 42.5 +/- 11.9, range 13-91 years) with bile duct injuries following laparoscopic cholecystectomy were reported. The most frequent lesions were main bile duct partial or total transection. The intraoperative mortality rate was 1/51 (1.9%) due to a complex biliary and vascular injury. The postoperative mortality rate of revision surgery was 5/50 (10%). T-tube positioning (n = 20) and Roux-en-Y hepato-jejunostomy (n = 20) were the procedures most frequently performed. The complication rate in patients treated with the T-tube was significantly higher than in those treated with hepatico-jejunostomy. Surgical treatment of biliary injuries following laparoscopic cholecystectomy was characterized by unusually high mortality and morbidity for a non-neoplastic disease. Roux-en-Y hepato-jejunostomy remains the procedure of choice for these injuries.

摘要

据报道,腹腔镜胆囊切除术导致医源性胆管损伤的发生率高于开腹手术。本研究的目的是提供一份关于腹腔镜胆囊切除术期间及术后胆道并发症的手术治疗及结果的多中心报告。向坎帕尼亚地区所有有腹腔镜胆囊切除术经验的外科医生邮寄了一份调查问卷。收集了1991年1月至2003年12月的数据。要求每位患者指出年龄、性别、相关疾病、病变部位和类型、手术经验、诊断、治疗及并发症情况。26位外科医生回答了问卷。报告了51例腹腔镜胆囊切除术后发生胆管损伤的患者(36例女性/15例男性;平均年龄:42.5±11.9岁,范围13 - 91岁)。最常见的损伤是胆总管部分或完全横断。由于复杂的胆道和血管损伤,术中死亡率为1/51(1.9%)。再次手术的术后死亡率为5/50(10%)。T管置入术(n = 20)和Roux - en - Y肝空肠吻合术(n = 20)是最常施行的手术。T管治疗患者的并发症发生率显著高于肝空肠吻合术治疗的患者。腹腔镜胆囊切除术后胆管损伤的手术治疗对于一种非肿瘤性疾病而言,其死亡率和发病率异常高。Roux - en - Y肝空肠吻合术仍然是这些损伤的首选手术方式。

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