两例卵巢颗粒细胞瘤中的14号染色体三体。
Trisomy 14 in two cases of granulosa cell tumor of the ovary.
作者信息
Górski G K, McMorrow L E, Blumstein L, Faasse D, Donaldson M H
机构信息
Department of Pediatrics, Cooper Hospital/University Medical Center, Camden, NJ 08103.
出版信息
Cancer Genet Cytogenet. 1992 Jun;60(2):202-5. doi: 10.1016/0165-4608(92)90020-9.
Cytogenetic analysis of granulosa cell tumor of the ovary was performed in two patients. G-banding analysis of cells cultured 3-5 days showed that the karyotype of each tumor contained normal diploid cells as well as cells with identical aberration: trisomy 14. This is the first report of trisomy 14 in two cases of granulosa cell tumor of the ovary. Flow cytometric DNA content analysis was also performed.
对两名卵巢颗粒细胞瘤患者进行了细胞遗传学分析。对培养3 - 5天的细胞进行G显带分析显示，每个肿瘤的核型都包含正常二倍体细胞以及具有相同畸变的细胞：14号染色体三体。这是两例卵巢颗粒细胞瘤中出现14号染色体三体的首次报道。同时也进行了流式细胞术DNA含量分析。
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