Kulchitsky K I, Talko V I
Acta Anat (Basel). 1979;104(4):394-9. doi: 10.1159/000145090.
Experiments were conducted on 100 dogs with creation of autovenous aortocoronary shunts in the coronary artery. The hearts were examined 1 year following surgery by routine histological, neurohistological, histochemical and electron-microscopic techniques. No severe destructive changes were revealed in the shunting system. The main process develop in the heart very early following surgery and consist in reactive changes in the intramural nerve elements, elevation of the phosphatase activity in the walls of the microcirculatory bed, redistribution of acid and neutral mucopolysaccharides and changes of permeability of the haematohistiocytic barriers; they are an adaptation response of the myocardium to operative stress and new conditions of influx of blood to the cardiac muscle.
对100只狗进行了实验，在冠状动脉中建立了自体静脉主动脉冠状动脉分流。术后1年，通过常规组织学、神经组织学、组织化学和电子显微镜技术对心脏进行检查。分流系统未发现严重的破坏性变化。主要过程在手术后很早就出现在心脏中，包括壁内神经元件的反应性变化、微循环床壁中磷酸酶活性的升高、酸性和中性粘多糖的重新分布以及血细胞组织屏障通透性的变化；它们是心肌对手术应激和心肌血液流入新条件的适应性反应。
