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对于大便失禁患者,在治疗括约肌缺陷时同时进行盆底修复是否有作用?

Is there a role for concomitant pelvic floor repair in patients with sphincter defects in the treatment of fecal incontinence?

作者信息

Steele Scott R, Lee Patrick, Mullenix Philip S, Martin Matthew J, Sullivan Eugene S

机构信息

General Surgery Service, Department of Surgery, Madigan Army Medical Center, Fort Lewis, WA 98431, USA.

出版信息

Int J Colorectal Dis. 2006 Sep;21(6):508-14. doi: 10.1007/s00384-005-0014-4. Epub 2005 Aug 2.

Abstract

BACKGROUND AND AIMS

More than half of all patients who undergo overlapping anal sphincter repair for fecal incontinence develop recurrent symptoms. Many have associated pelvic floor disorders that are not surgically addressed during sphincter repair. We evaluate the outcomes of combined overlapping anal sphincteroplasty and pelvic floor repair (PFR) vs. anterior sphincteroplasty alone in patients with concomitant sphincter and pelvic floor defects.

PATIENTS AND METHODS

We reviewed all patients with concomitant defects who underwent surgery between February 1998 and August 2001. Patients were assessed preoperatively by anorectal manometry, pudendal nerve terminal motor latency, and endoanal ultrasound. The degree of continence was assessed both preoperatively and postoperatively using the Cleveland Clinic Florida fecal incontinence score. Postoperative success was defined as a score of <or=5, whereas postoperative quality of life was assessed by a standardized questionnaire.

RESULTS

Twenty-eight patients (mean age 52.3 years) underwent overlapping anal sphincteroplasty. The mean follow-up was 33.8 months. Cleveland Clinic Florida scores postoperatively showed a significant improvement from preoperative values (14.2 vs 5.1, p<0.001). Seventeen patients (61%) underwent concomitant PFR with sphincteroplasty. Three patients (27%) without PFR and one patient (6%) with PFR underwent repeat sphincter repair due to worsening symptoms (p=0.15). Two patients with PFR and one patient without PFR ultimately had an ostomy due to a failed repair (p=0.66). Comparing patients with and without PFR, there was a trend toward higher success rates (71 vs. 45%) when pelvic prolapse issues were addressed during sphincter repair.

CONCLUSION

Concomitant evaluation and repair of pelvic floor prolapse may be a clinically significant component of a successful anal sphincteroplasty for fecal incontinence but warrant further prospective evaluation.

摘要

背景与目的

超过半数接受重叠式肛门括约肌修补术治疗大便失禁的患者会出现复发症状。许多患者伴有盆底功能障碍,而在括约肌修补术中未对其进行手术处理。我们评估了重叠式肛门括约肌成形术联合盆底修复术(PFR)与单纯前路括约肌成形术在伴有括约肌和盆底缺陷患者中的治疗效果。

患者与方法

我们回顾了1998年2月至2001年8月间所有接受手术治疗的伴有缺陷的患者。术前通过肛门直肠测压、阴部神经终末运动潜伏期和肛管超声对患者进行评估。术前和术后均使用克利夫兰诊所佛罗里达大便失禁评分评估控便程度。术后成功定义为评分≤5分,而术后生活质量通过标准化问卷进行评估。

结果

28例患者(平均年龄52.3岁)接受了重叠式肛门括约肌成形术。平均随访时间为33.8个月。术后克利夫兰诊所佛罗里达评分较术前值有显著改善(14.2对5.1,p<0.001)。17例患者(61%)在括约肌成形术的同时接受了PFR。3例未接受PFR的患者(27%)和1例接受PFR的患者(6%)因症状恶化接受了再次括约肌修补术(p=0.15)。2例接受PFR的患者和1例未接受PFR的患者最终因修补失败而行造口术(p=0.66)。比较接受和未接受PFR的患者,在括约肌修补术中处理盆腔脏器脱垂问题时,成功率有升高趋势(71%对45%)。

结论

盆底脱垂的联合评估与修复可能是大便失禁成功肛门括约肌成形术的一个具有临床意义的组成部分,但需要进一步的前瞻性评估。

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