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[糖尿病昏迷尸检诊断中眼玻璃体的生化分析]

[Biochemical analysis of the vitreous body of the eye in post-mortem diagnosis of diabetic coma].

作者信息

Terekhina N A, Akimov P A

出版信息

Patol Fiziol Eksp Ter. 2005 Apr-Jun(2):24-5.

Abstract

The biochemical test of the vitreous body (VB) may be used in post-mortem diagnosis of diabetes mellitus and diabetic coma. Concentrations of glucose, lactate, keton bodies in the VB of the eye do not depend on duration of post-mortem period. Methods of diagnosis of hyperglycemic, hypoglycemic and ketoacidotic comas in the postmortem period are proposed. VB glucose over 17 mmol/l is a specific marker indicating death due to diabetic coma with hyperglycemia. Blood lactate under 16 mmol/l and glucose absence in the VB specifically mark death of hypoglycemic coma. In death of diabetic coma with ketoacidosis, a sharp rise in the level of VB ketonic bodies was observed.

摘要

玻璃体的生化检测可用于糖尿病及糖尿病昏迷的尸检诊断。眼玻璃体中葡萄糖、乳酸、酮体的浓度与死后时间长短无关。本文提出了死后高血糖、低血糖和酮症酸中毒昏迷的诊断方法。玻璃体葡萄糖浓度超过17 mmol/l是糖尿病高血糖昏迷致死的特异性标志物。玻璃体中血乳酸低于16 mmol/l且无葡萄糖是低血糖昏迷致死的特异性标志。在糖尿病酮症酸中毒昏迷死亡病例中,观察到玻璃体酮体水平急剧升高。

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