Shao Qiang, Song Jian, Guo Yu-wen, Lu Wen-cheng, Du Lin-dong
Department of Urology, Beijing Friendship Hospital, Capital University of Medicine, Beijing 100050, China.
Zhonghua Nan Ke Xue. 2005 Jul;11(7):505-7.
To evaluate the degree of sexual dysfunction in an unselected population of men with benign prostatic hyperplasia (BPH) accompanied by lower urinary tract symptoms (LUTS), and to assess the correlation between sexual dysfunction and urinary symptoms and age.
A total of 88 men with symptomatic BPH were investigated using the International Prostate Symptom Score (IPSS), International Index of Erectile Function-5 (IIEF-5), Brief Sexual Function Inventory (BSFI), and the measurement of urinary flow rate, the total prostatic volume and serum testosterone. Regression analysis was used to determine the correlation among the variables.
The mean age of the patients was (67.90 +/- 7.59) years, the mean IPSS score was (18.4 +/- 7. 79), and the mean IIEF-5 was (8.50 +/- 8.98). There were 76 cases of erectile dysfunction (86.36%). Among the BSFI scores, the mean sexual drive score was (1.92 +/- 2.21), the mean erectile function score was (4.18 +/- 4.96), the mean ejaculation score was (2.55 +/- 3.57), the mean problem assessment score was (10.44 +/- 3.57), and the mean overall satisfaction score was (1.90 +/- 1.37). Among the 88 cases, 65 (72.86%) had poor sexual drive, 70 (79.55%) erectile dysfunction, and 60 (68.18%) poor ejaculation. There was statistically significant correlation between age and sexual symptom scores for erection (gamma = -0.552, P = 0.000), IIEF-5 scores (gamma = - 0.567, P = 0.000), and IPSS (gamma = 0.213, P = 0.047) as well as between IPSS and sexual symptom scores for erection and overall satisfaction (gamma = -0.332, P = 0.002 and gamma = -0.302, P = 0.005). IIEF-5 scores were significantly correlated with sexual symptom scores for each of the three categories (sexual drive, erection and ejaculation) (P < 0.05). Serum testosterone did not correlate to age, IIEF-5 scores and sexual function (P > 0.05), nor did peak urinary flow rate and total prostatic volume to IPSS, IIEF-5 scores and sexual function (P > 0.05).
Results of this study suggest that age and LUTS are risk factors of sexual function, and sexual dysfunction is closely related to the severity of LUTS.
评估未经选择的伴有下尿路症状（LUTS）的良性前列腺增生（BPH）男性人群的性功能障碍程度，并评估性功能障碍与尿路症状及年龄之间的相关性。
采用国际前列腺症状评分（IPSS）、国际勃起功能指数-5（IIEF-5）、简要性功能量表（BSFI）对88例有症状的BPH男性进行调查，并测量尿流率、前列腺总体积和血清睾酮。采用回归分析确定各变量之间的相关性。
患者的平均年龄为（67.90±7.59）岁，平均IPSS评分为（18.4±7.79），平均IIEF-5评分为（8.50±8.98）。勃起功能障碍76例（86.36%）。在BSFI评分中，平均性欲评分为（1.92±2.21），平均勃起功能评分为（4.18±4.96），平均射精评分为（2.55±3.57），平均问题评估评分为（10.44±3.57），平均总体满意度评分为（1.90±1.37）。88例中，65例（72.86%）性欲低下，70例（79.55%）勃起功能障碍，60例（68.18%）射精功能差。年龄与勃起性功能症状评分（γ=-0.552，P=0.000）、IIEF-5评分（γ=-0.567，P=0.000）、IPSS（γ=0.213，P=0.047）之间以及IPSS与勃起性功能症状评分和总体满意度之间（γ=-0.332，P=0.002和γ=-0.302，P=0.005）存在统计学显著相关性。IIEF-5评分与三个类别（性欲、勃起和射精）中的每一个性功能症状评分均显著相关（P<0.05）。血清睾酮与年龄、IIEF-5评分和性功能无关（P>0.05），尿流率峰值和前列腺总体积与IPSS、IIEF-5评分和性功能也无关（P>0.05）。
本研究结果表明，年龄和LUTS是性功能的危险因素，性功能障碍与LUTS的严重程度密切相关。
