[50岁及以上男性下尿路症状与勃起功能障碍的相关性]

[Correlation of lower urinary tract symptoms with erectile dysfunction in men aged 50 years and above].

作者信息

Wang Yi, Sun Guo-feng, He Li-jun, Meng Jun, Wu Shi-liang, Xiao Yun-xiang, Li Xue-song, Na Yan-qun

机构信息

Department of Urology, Shougang Hospital, Peking University, Beijing 100041, China.

出版信息

Zhonghua Nan Ke Xue. 2008 Jun;14(6):517-20.

PMID:18649749

Abstract

OBJECTIVE

To investigate the incidence of lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) in men aged > or = 50 years and to achieve the correlation between LUTS (obstructive symptoms and stimulant symptoms) and ED.

METHODS

We investigated 245 men aged > or = 50 years and with regular sex mates using International Prostate Symptom Score (IPSS) and International Index of Erectile Function-5 (IIEF-5), designed diagnostic interrogation and medical examination, and statistically analyzed the results of IPSS, IIEF-5, LUTS and their correlation with erectile function.

RESULTS

The incidence of ED was 81.9% (140/171) among the men with LUTS, 73.1% (38/52), 82.1% (46/56) and 88.9% (56/63) respectively in the 50-59, 60-69 and > or = 70 age groups, with significant differences in IPSS, IIEF-5 (P < 0.01) and the severity of ED (P < 0.01) among different age groups. ED incidence was found significantly correlated with the severity of LUTS (r = 0.52, P < 0.01), 71.3% (57/80), 89.6% (60/67) and 95.8% (23/24) respectively in the groups of mild, moderate and severe LUTS. The mean scores on obstructive and stimulant symptoms were (3.1 +/- 3.6) and (6.8 +/- 4.9), and their correlation coefficients with IIEF-5 were r = -0.41 (P < 0.01) and r = -0.59 (P < 0.01), respectively.

CONCLUSION

The incidence of ED is high in men with LUTS and positively correlated with the severity of LUTS. Stimulant symptoms have greater influence than obstructive symptoms on the sexual life of old and middle-aged males.

摘要

目的

调查年龄≥50岁男性下尿路症状（LUTS）及勃起功能障碍（ED）的发生率，并探讨LUTS（梗阻性症状和刺激性症状）与ED之间的相关性。

方法

采用国际前列腺症状评分（IPSS）和国际勃起功能指数-5（IIEF-5），对245例年龄≥50岁且有规律性伴侣的男性进行调查，设计诊断性问诊及体格检查，并对IPSS、IIEF-5结果、LUTS及其与勃起功能的相关性进行统计学分析。

结果

LUTS男性中ED发生率为81.9%（140/171），50-59岁、60-69岁及≥70岁年龄组分别为73.1%（38/52）、82.1%（46/56）和88.9%（56/63），不同年龄组IPSS、IIEF-5（P<0.01）及ED严重程度（P<0.01）差异有统计学意义。ED发生率与LUTS严重程度显著相关（r=0.52，P<0.01），轻度、中度和重度LUTS组分别为71.3%（57/80）、89.6%（60/67）和95.8%（23/24）。梗阻性和刺激性症状的平均得分分别为（3.1±3.6）和（6.8±4.9），它们与IIEF-5的相关系数分别为r=-0.41（P<0.01）和r=-0.59（P<0.