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[咯血作为白塞病的一种并发症]

[Haemoptysis as a complication of Behçet's disease].

作者信息

van den Brand J J G, van den Bosch J M M, Seldenrijk C A, Dercksen M W, Ruitenberg H M, Schramel F M N H

机构信息

St. Antonius Ziekenhuis, Postbus 2500, 3430 EM, Nieuwegein.

出版信息

Ned Tijdschr Geneeskd. 2005 Jul 16;149(29):1631-5.

Abstract

Three patients, two Moroccan men aged 27 and 25 and a Turkish man aged 25, presented with haemoptysis caused by pulmonary aneurysm. The aneurysms had formed as a complication of Behçet's disease. Two of them were treated with high doses of corticosteroids. One man recovered and another died as a consequence of massive haemoptysis. The third man underwent emergency thoracotomy and pneumectomy due to massive haemoptysis. Postoperatively he was treated with cyclosporine resulting in full recovery. Behçet's disease is a multisystem vasculitis characterised by orogenital ulcerations and uveitis. In a minority of cases pulmonary aneurysms develop, often causing massive haemoptysis. Aneurysms are often accompanied by venous thrombosis. Treatment consists of immunosuppressive therapy. Nevertheless a considerable number of patients die following massive haemoptysis.

摘要

三名患者,两名分别为27岁和25岁的摩洛哥男子以及一名25岁的土耳其男子,因肺动脉瘤出现咯血症状。这些动脉瘤是白塞病的并发症。其中两人接受了大剂量皮质类固醇治疗。一人康复,另一人因大量咯血死亡。第三名男子因大量咯血接受了急诊开胸手术和肺切除术。术后他接受了环孢素治疗,最终完全康复。白塞病是一种多系统血管炎,其特征为口腔生殖器溃疡和葡萄膜炎。在少数情况下会出现肺动脉瘤,常导致大量咯血。动脉瘤常伴有静脉血栓形成。治疗包括免疫抑制疗法。然而,相当多的患者在大量咯血后死亡。

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