Kobori M, Hosoyamada A, Fukasawa K, Gomi K
Department of Anesthesiology, School of Medicine, Showa University, Tokyo.
Masui. 1992 May;41(5):721-6.
Dividing anesthesia for gynecological laparotomy into nitrous oxide-oxygen-halothane (GOF) anesthesia (group A), nitrous oxide-oxygen (GO) plus ketamine anesthesia (group B) and GOF plus epidural anesthesia (group C), we studied effects of each anesthesia on circulatory and metabolic systems. During the operation, influence on the heart rate was slight in three groups, while systolic pressure decreased significantly in group C. The lactic acid in the blood was elevated in three groups, but the elevation was least in group C. The elevation of lactic acid pyruvic acid ratio (L/P) was less in group C. The blood glucose level was elevated significantly in three groups, and it was highest in group A. On the other hand NEFA was elevated significantly in group A, while no change was noted in group B, and decreasing was noted in group C. The results indicate that no large influence of each anesthesia on the metabolic system was noted in group A and B, and its influence was the least in group C.
将妇科剖腹手术的麻醉分为氧化亚氮-氧气-氟烷（GOF）麻醉（A组）、氧化亚氮-氧气（GO）加氯胺酮麻醉（B组）和GOF加硬膜外麻醉（C组），我们研究了每种麻醉对循环和代谢系统的影响。手术期间，三组对心率的影响轻微，而C组收缩压显著下降。三组血液中的乳酸均升高，但C组升高最少。C组乳酸丙酮酸比值（L/P）升高较少。三组血糖水平均显著升高，A组最高。另一方面，A组游离脂肪酸（NEFA）显著升高，B组无变化，C组下降。结果表明，A组和B组每种麻醉对代谢系统均无较大影响，C组影响最小。
