Lacoumenta S, Walsh E S, Waterman A E, Ward I, Paterson J L, Hall G M
Br J Anaesth. 1984 May;56(5):493-7. doi: 10.1093/bja/56.5.493.
The effects of ketamine anaesthesia on the metabolic and endocrine response to pelvic surgery were investigated, and compared with results obtained in a control group of patients anaesthetized with thiopentone and halothane. Ketamine anaesthesia before the onset of surgery was associated with a significant increase in blood glucose and plasma cortisol concentrations, and in heart rate. However, when surgery was established there were no metabolic, endocrine or haemodynamic differences between ketamine and halothane anaesthesia. We conclude that ketamine does not exacerbate the metabolic response to surgery.
研究了氯胺酮麻醉对盆腔手术代谢和内分泌反应的影响，并与硫喷妥钠和氟烷麻醉的对照组患者的结果进行了比较。手术开始前的氯胺酮麻醉与血糖、血浆皮质醇浓度和心率的显著升高有关。然而，当手术开始后，氯胺酮麻醉和氟烷麻醉之间在代谢、内分泌或血流动力学方面没有差异。我们得出结论，氯胺酮不会加剧手术的代谢反应。
