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[大剂量芬太尼麻醉诱导期间的脑电图变化——通过LIFESCAN脑电图监测仪进行评估]

[Electroencephalographic change during induction of high-dose fentanyl anesthesia--evaluation by LIFESCAN EEG monitor].

作者信息

Ochiai R, Sato K, Koitabashi T, Takeda J, Sekiguchi H, Fukushima K

机构信息

Department of Anesthesiology, School of Medicine, Keio University, Tokyo.

出版信息

Masui. 1992 May;41(5):799-804.

PMID:1608157
Abstract

The relation between the patient's consciousness level and the change in electroencephalographic (EEG) activity during general anesthesia has not been well understood. In the present study, we evaluated such relationship quantitatively during the induction of high-dose fentanyl anesthesia in adult open-heart cases. There are significant increase in delta activity and significant decrease in alpha and beta activity in response to the induction of anesthesia. The loss of consciousness coincided with the sharp reduction in delta ratio and edge frequency (80%). Such reduction was more prominent in delta ratio than in edge frequency. These findings suggest that delta ratio could indicate the consciousness level during the induction of high-dose fentanyl anesthesia. Further study is needed to clarify the EEG response during inhalation and intravenous anesthesia in relation to EEG activity.

摘要

全身麻醉期间患者意识水平与脑电图(EEG)活动变化之间的关系尚未得到充分理解。在本研究中,我们在成人心脏直视手术病例的高剂量芬太尼麻醉诱导过程中对这种关系进行了定量评估。麻醉诱导后,δ波活动显著增加,α波和β波活动显著减少。意识丧失与δ波比率和边缘频率(80%)的急剧下降同时发生。这种下降在δ波比率中比在边缘频率中更为明显。这些发现表明,δ波比率可指示高剂量芬太尼麻醉诱导期间的意识水平。需要进一步研究以阐明吸入麻醉和静脉麻醉期间与EEG活动相关的EEG反应。

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