Takatori M, Uchida H, Takeuchi M, Mikane T, Yoshioka M, Kurasako T, Muto J, Matsumoto M, Tada K
Masui. 1989 Jan;38(1):33-40.
Twenty-one patients who underwent cardiac surgery were assigned to receive high-dose fentanyl rapid sequence anesthesia or conventional high-dose fentanyl anesthesia. In conventional method group, power of delta wave decreased with respect to time. But in rapid sequence group, no decrease was seen until the end of operation. Good maintenance of delta wave in rapid sequence group may be achieved by higher plasma fentanyl concentration and the absence of acute tolerance. In conclusion, high-dose fentanyl rapid sequence anesthesia is a useful method for cardiac surgery.
21例接受心脏手术的患者被分配接受高剂量芬太尼快速序贯麻醉或传统高剂量芬太尼麻醉。在传统方法组中，δ波功率随时间下降。但在快速序贯组中，直到手术结束才出现下降。快速序贯组中δ波的良好维持可能是通过较高的血浆芬太尼浓度和无急性耐受性实现的。总之，高剂量芬太尼快速序贯麻醉是心脏手术的一种有用方法。
