Tanawattanacharoen Somchai, Manotaya Saknan, Wacharaprechanont Teera, Uerpairojkit Boonchai, Tannirandorn Yuen, Charoenvidhya Dhirapongs
Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, Bangkok 10330, Thailand.
J Med Assoc Thai. 2004 Sep;87 Suppl 2:S284-7.
Acardiac twin is a rare event with high perinatal mortality rate and the management strategies remain controversial. The authors report 4 cases of twin pregnancies associated with one acardiac twin diagnosed at King Chulalongkorn Memorial Hospital during the period 1993 to 2002. Two cases were expectantly managed and intrauterine interventions were performed in order to occlude umbilical artery of the acardiac twin in 2 cases, by using Guglielmi detachable coil (GDC) embolization and absolute alcohol injection. Overall, the perinatal mortality rate for the pump twin was 50% and the survival rate of expectant management in the present series was 100%. GDC embolization was judged to be technically successful since it completely occluded the circulation to the acardiac twin. However, the pump twin was dead which might have resulted from the compromised state due to cardiac failure. At present, it seems that conservative management with close antenatal surveillance is the treatment of choice when the twin-weight ratios are substantially less than 70%. Invasive techniques should be considered when there is ultrasound evidence of hydramnios or congestive heart failure of the pump twin at a previable gestational age.
无心畸胎是一种罕见情况,围产期死亡率很高,其管理策略仍存在争议。作者报告了1993年至2002年期间在朱拉隆功国王纪念医院诊断出的4例双胎妊娠合并无心畸胎病例。2例采用期待治疗,另外2例通过使用 Guglielmi 可脱性弹簧圈(GDC)栓塞术和无水乙醇注射进行宫内干预,以阻断无心畸胎的脐动脉。总体而言,供血儿的围产期死亡率为50%,本系列中期待治疗的存活率为100%。GDC栓塞术在技术上被判定为成功,因为它完全阻断了流向无心畸胎的循环。然而,供血儿死亡,这可能是由于心力衰竭导致的身体状况受损所致。目前,当双胎体重比显著低于70%时,似乎选择密切产前监测的保守治疗方法。当在可存活孕周前超声显示有羊水过多或供血儿充血性心力衰竭的证据时,应考虑采用侵入性技术。