Chen Jia-Jin Jason, Wu Yi-Ning, Huang Sheng-Chih, Lee Hsin-Min, Wang Yu-Lin
Institute of Biomedical Engineering, National Cheng Kung University, Taiwan, ROC.
Arch Phys Med Rehabil. 2005 Aug;86(8):1655-60. doi: 10.1016/j.apmr.2005.03.019.
To use a portable muscle tone assessment device to measure spasticity after a botulinum toxin type A (BTX-A) injection.
Before-after trial.
Hospital.
Ten chronic stroke patients with upper-limb spasticity.
BTX-A was injected in the biceps brachii.
The biomechanic parameters, viscous component, and averaged viscosity derived from the acquired reactive resistance and angular displacements, as well as the reflex electromyographic threshold of biceps brachii, were used for spasticity evaluation.
A statistically significant decrease in averaged viscosity and a significant increase in reflex electromyographic threshold (P<.05) both indicated reduction in spasticity owing to BTX-A intervention. There was no clear reflex electromyographic activity detected at lower stretch frequencies.
Our portable design allows for the convenient use of the device for quantifying spasticity in clinics. All quantitative measurements suggest that BTX-A decreases spasticity within 2 weeks of injection. Our portable muscle tone measurement device may be useful for the clinical assessment of elbow flexor spasticity.
使用便携式肌张力评估设备测量A型肉毒毒素（BTX-A）注射后的痉挛程度。
前后对照试验。
医院。
10名患有上肢痉挛的慢性中风患者。
在肱二头肌中注射BTX-A。
利用从获得的反应性阻力和角位移得出的生物力学参数、粘性成分和平均粘度，以及肱二头肌的反射性肌电图阈值来评估痉挛程度。
平均粘度有统计学意义的降低以及反射性肌电图阈值显著升高（P<0.05）均表明BTX-A干预使痉挛程度降低。在较低的拉伸频率下未检测到明显的反射性肌电图活动。
我们的便携式设计使该设备在临床中便于用于量化痉挛程度。所有定量测量结果均表明BTX-A在注射后2周内可减轻痉挛。我们的便携式肌张力测量设备可能有助于肘部屈肌痉挛的临床评估。
