Leuschner Philipp J F, Obernosterer Gregor, Martinez Javier
Institute of Molecular Biotechnology of the Austrian Academy of Sciences, IMBA, Vienna, Austria.
Curr Biol. 2005 Aug 9;15(15):R603-5. doi: 10.1016/j.cub.2005.07.044.
In Drosophila, Dicer-2 requires the double-stranded RNA binding protein R2D2, to mediate the assembly of short interfering RNAs into the RNA-induced silencing complex. New data show that Dicer-1 also requires a double-stranded RNA binding protein called Loquacious for efficient microRNA-mediated gene silencing.
在果蝇中，Dicer-2 需要双链 RNA 结合蛋白 R2D2 来介导短干扰 RNA 组装成 RNA 诱导沉默复合体。新数据表明，Dicer-1 高效介导 microRNA 介导的基因沉默也需要一种名为 Loquacious 的双链 RNA 结合蛋白。
