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本文引用的文献

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Treating head lice.治疗头虱。
BMJ. 2003 Jun 7;326(7401):1256-7. doi: 10.1136/bmj.326.7401.1256.
2
Wet combing for head lice: feasibility in mass screening, treatment preference and outcome.湿梳法治疗头虱：大规模筛查的可行性、治疗偏好及效果
J R Soc Med. 2002 Jul;95(7):348-52. doi: 10.1177/014107680209500707.
3
Head lice: is there a solution?头虱：有解决办法吗？
Curr Opin Infect Dis. 2000 Apr;13(2):135-139. doi: 10.1097/00001432-200004000-00007.
4
Widespread insecticide resistance in head lice to the over-the-counter pediculocides in England, and the emergence of carbaryl resistance.英国头虱对非处方灭虱药产生广泛抗药性，且西维因抗药性出现。
Br J Dermatol. 2002 Jan;146(1):88-93. doi: 10.1046/j.1365-2133.2002.04473.x.
5
Interventions for treating head lice.治疗头虱的干预措施。
Cochrane Database Syst Rev. 2001(2):CD001165. doi: 10.1002/14651858.CD001165.
6
The methodology and operation of a pilot randomized control trial of the effectiveness of the Bug Busting method against a single application insecticide product for head louse treatment.一项关于“灭虱法”与单一应用杀虫剂产品治疗头虱效果对比的试点随机对照试验的方法与操作。
Public Health. 2000 Jul;114(4):265-8. doi: 10.1038/sj.ph.1900645.
7
Comparison of wet combing with malathion for treatment of head lice in the UK: a pragmatic randomised controlled trial.英国湿梳法与马拉硫磷治疗头虱的比较：一项实用随机对照试验。
Lancet. 2000 Aug 12;356(9229):540-4. doi: 10.1016/s0140-6736(00)02578-2.
8
Evidence for double resistance to permethrin and malathion in head lice.头虱对氯菊酯和马拉硫磷双重耐药的证据。
Br J Dermatol. 1999 Sep;141(3):508-11. doi: 10.1046/j.1365-2133.1999.03046.x.
9
Head lice resistant to pyrethroid insecticides in Britain.英国出现对拟除虫菊酯类杀虫剂有抗性的头虱。
BMJ. 1995 Sep 16;311(7007):752. doi: 10.1136/bmj.311.7007.752.
10
Systematic review of clinical efficacy of topical treatments for head lice.头虱局部治疗临床疗效的系统评价
BMJ. 1995 Sep 2;311(7005):604-8. doi: 10.1136/bmj.311.7005.604.

在英国进行的关于Bug Buster套装与非处方灭虱药治疗头虱的单盲、随机、对照研究。

Single blind, randomised, comparative study of the Bug Buster kit and over the counter pediculicide treatments against head lice in the United Kingdom.

作者信息

Hill N, Moor G, Cameron M M, Butlin A, Preston S, Williamson M S, Bass C

机构信息

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT.

出版信息

BMJ. 2005 Aug 13;331(7513):384-7. doi: 10.1136/bmj.38537.468623.E0. Epub 2005 Aug 5.

DOI:10.1136/bmj.38537.468623.E0
PMID:16085658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1184251/
Abstract

OBJECTIVE

To compare the effectiveness of the Bug Buster kit with a single treatment of over the counter pediculicides for eliminating head lice.

DESIGN

Single blind, multicentre, randomised, comparative clinical study.

SETTING

Four counties in England and one county in Scotland.

PARTICIPANTS

133 young people aged 2-15 years with head louse infestation: 56 were allocated to the Bug Buster kit and 70 to pediculicide treatment.

INTERVENTIONS

Home use of proprietary pediculicides (organophosphate or pyrethroid) or the Bug Buster kit.

MAIN OUTCOME MEASURE

Presence of head lice 2-4 days after end of treatment: day 5 for the pediculicides and day 15 for the Bug Buster kit.

RESULTS

The cure rate using the Bug Buster kit was significantly greater than that for the pediculicides (57% v 13%; relative risk 4.4, 95% confidence interval 2.3 to 8.5). Number needed to treat for the Bug Buster kit compared with the pediculicides was 2.26.

CONCLUSION

The Bug Buster kit was the most effective over the counter treatment for head louse infestation in the community when compared with pediculicides.

摘要

目的

比较“灭虱宝套装”与单次使用非处方灭虱药消除头虱的效果。

设计

单盲、多中心、随机、对照临床研究。

地点

英格兰的四个郡和苏格兰的一个郡。

参与者

133名2至15岁的头虱感染者：56人被分配使用“灭虱宝套装”，70人接受灭虱药治疗。

干预措施

在家使用专利灭虱药（有机磷或拟除虫菊酯）或“灭虱宝套装”。

主要观察指标

治疗结束后2至4天（灭虱药治疗为第5天，“灭虱宝套装”为第15天）头虱的存在情况。

结果

使用“灭虱宝套装”的治愈率显著高于使用灭虱药（57%对13%；相对危险度4.4，95%置信区间2.3至8.5）。与灭虱药相比，“灭虱宝套装”的需治人数为2.26。

结论

与灭虱药相比，“灭虱宝套装”是社区中治疗头虱感染最有效的非处方治疗方法。