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阿尔茨海默病中词汇信息的内隐记忆保存情况。

Preserved implicit memory for lexical information in Alzheimer's disease.

作者信息

Perfect T J, Downes J J, De Mornay Davies P, Wilson K

机构信息

Department of Psychology, University of Liverpool, England.

出版信息

Percept Mot Skills. 1992 Jun;74(3 Pt 1):747-54. doi: 10.2466/pms.1992.74.3.747.

Abstract

Recent studies have suggested that there is a specific impairment of implicit memory for lexical priming in Alzheimer's Disease. However, there are problems in accepting data from the word-stem completion paradigm as evidence of pure implicit-memory performance. To assess whether Alzheimer's Disease patients are relatively impaired on implicit memory for lexical information an anagram-solution task was adopted. A group of 16 early stage Alzheimer's Disease patients and a group of 16 normal elderly subjects were presented a list of 40 target words. Subsequent free recall was significantly poorer in the former group, but while both groups were significantly better at solving anagrams for words they had previously seen, there was no difference between the two groups in the amount of priming. The data are consistent with the view that previous reports of an implicit deficit in Alzheimer's Disease may not generalise to implicit tasks independent of explicit-memory performance.

摘要

近期研究表明,阿尔茨海默病患者在词汇启动的内隐记忆方面存在特定损伤。然而,将词干补全范式的数据作为纯内隐记忆表现的证据存在问题。为了评估阿尔茨海默病患者在词汇信息的内隐记忆方面是否相对受损,采用了字谜解决任务。向一组16名早期阿尔茨海默病患者和一组16名正常老年受试者呈现了40个目标单词的列表。前一组随后的自由回忆明显较差,但两组在解决他们之前见过的单词的字谜方面都明显更好,两组之间的启动量没有差异。这些数据与以下观点一致,即先前关于阿尔茨海默病内隐缺陷的报告可能不适用于独立于外显记忆表现的内隐任务。

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