Akyol F H, Atahan I L, Zorlu F, Gürkaynak M, Alanyali H, Ozyar E
Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Radiother Oncol. 1992 Apr;23(4):245-8. doi: 10.1016/s0167-8140(92)80129-7.
43 Patients with the diagnosis of cerebellar astrocytoma were post-operatively treated, between 1 January 1976 and 31 December 1985. Their age ranged between 2 and 51 years with a median of 13. There were 22 males and 21 females. The tumours were reported as grade I in 18, and grade II in 25 patients. The primary surgical intervention was in the form of biopsy in 3, subtotal excision in 24 and macroscopic total excision in 16. All patients were treated with cobalt-60 teletherapy unit, to a total tumour dose of 4500-5500 cGy in 6-7 weeks. The obtained 5 and 10 year actuarial survival rates are 78% and 78%. Our study gives the impression that, age, sex and tumour grade are not determining factors in survival and post-operative radiotherapy improves prognosis in cases treated by subtotal excision while it remains unnecessary in those who had undergone total surgical removal.
1976年1月1日至1985年12月31日期间,43例被诊断为小脑星形细胞瘤的患者接受了术后治疗。他们的年龄在2岁至51岁之间,中位数为13岁。其中男性22例,女性21例。据报告,18例肿瘤为I级,25例为II级。初次手术干预方式为3例活检、24例次全切除和16例肉眼全切。所有患者均接受钴-60远距离治疗,在6至7周内给予肿瘤总剂量4500 - 5500 cGy。获得的5年和10年精算生存率均为78%。我们的研究表明,年龄、性别和肿瘤分级不是生存的决定因素,术后放疗可改善次全切除病例的预后,而对于接受了完全手术切除的患者则无必要。