乌拉坦诱导的小鼠肺肿瘤中四种糖酵解酶（己糖激酶、磷酸果糖激酶、丙酮酸激酶和乳酸脱氢酶）的活性及乳酸脱氢酶的同工酶谱。
Activities of four glycolytic enzymes (HK, PFK, PK, and LDH) and isozymic pattern of LDH in mouse lung tumor induced by urethan.
作者信息
Rády P, Arany I, Boján F, Kertai P
出版信息
J Cancer Res Clin Oncol. 1979;95(3):287-9. doi: 10.1007/BF00410650.
Abstract
In the lungs of CFLP mice the activities of glycolytic key enzymes (HK, PFK, PK) and LDH as well as LDH isozymic pattern change in the course of life. The activities of these glycolytic enzymes in the lung tumors induced by urethan in CFLP mice are significantly higher than those in the normal adult lung and they are similar to those in the normal fetal lung. The isozymic pattern of LDH of pulmonary adenomas resembles that of the normal fetal lung, too.
摘要
在CFLP小鼠的肺中，糖酵解关键酶（己糖激酶、磷酸果糖激酶、丙酮酸激酶）和乳酸脱氢酶的活性以及乳酸脱氢酶同工酶模式在生命过程中会发生变化。氨基甲酸乙酯诱导的CFLP小鼠肺肿瘤中这些糖酵解酶的活性显著高于正常成年肺中的活性，且与正常胎儿肺中的活性相似。肺腺瘤的乳酸脱氢酶同工酶模式也类似于正常胎儿肺的同工酶模式。
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