胺类在水中对环氧化合物的高化学选择性加成反应。
Highly chemoselective addition of amines to epoxides in water.
作者信息
Azizi Najmodin, Saidi Mohammad R
机构信息
Department of Chemistry, Sharif University of Technology, P.O. Box 11465-9516, Tehran, Iran.
出版信息
Org Lett. 2005 Aug 18;7(17):3649-51. doi: 10.1021/ol051220q.
PMID:16092841
Abstract
Aminolysis of a variety of epoxides by aliphatic and aromatic amines in water, in the absence of any catalyst with high yields, is reported. Beta-amino alcohols were formed under mild conditions with high selectivity and in excellent yields. [reaction: see text]
摘要
据报道，在水中，在无任何催化剂的情况下，脂肪族和芳香族胺能以高收率对多种环氧化物进行氨解反应。在温和条件下以高选择性和优异收率生成了β-氨基醇。[反应：见正文]
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