Tseng Yen-Ju, Ahmed Atallah F, Dai Chang-Feng, Chiang Michael Y, Sheu Jyh-Horng
Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Org Lett. 2005 Aug 18;7(17):3813-6. doi: 10.1021/ol051513j.
An unprecedented C,C-linked dimeric norcembranoid (sinulochmodin A, 1), a novel isocembranoid (sinulochmodin B, 2), and a novel yonarane norditerpenoid (sinulochmodin C, 3) were isolated from the soft coral Sinularia lochmodes. The structures of these metabolites were elucidated by extensive spectroscopic analysis and on the basis of the absolute structures of two related norditerpenoids (4 and 5), which were determined for the first time by a modified Mosher method. A plausible pathway for the biosynthesis of 1 and 3-5 from 2 was postulated. [structure: see text]
从软珊瑚Sinularia lochmodes中分离出了一种前所未有的C,C-连接二聚降蒈二萜（sinulochmodin A，1）、一种新型异蒈二萜（sinulochmodin B，2）和一种新型yonarane北二萜（sinulochmodin C，3）。通过广泛的光谱分析并基于两种相关北二萜（4和5）的绝对结构（首次通过改良的Mosher方法确定）阐明了这些代谢产物的结构。推测了从2生物合成1以及3至5的可能途径。[结构：见正文]
