Zaoutis Theoklis E, Coffin Susan E, Chu Jaclyn H, Heydon Kateri, Zhao Huaqing, Greves H Mollie, Walsh Thomas J
Division of Infectious Diseases, The Children's Hospital of Philadelphia, PA 19104, USA.
Pediatr Infect Dis J. 2005 Aug;24(8):736-9. doi: 10.1097/01.inf.0000172938.76561.8e.
We performed a retrospective cohort study of hospitalized children with positive blood cultures for Candida species. Independent risk factors for mortality by multivariable analysis were location in the pediatric intensive care unit at the time of infection (hazard ratio, 6.3; 95% confidence interval, 1.6-24.3) and the presence of an arterial catheter (hazard ratio, 2.4; 95% confidence interval, 1.1-5.8). Our findings help identify a group of pediatric patients that should be targeted for future interventions to prevent and treat candidemia.
我们对血培养念珠菌属呈阳性的住院儿童进行了一项回顾性队列研究。通过多变量分析得出的死亡独立危险因素为感染时位于儿科重症监护病房(风险比,6.3;95%置信区间,1.6 - 24.3)以及存在动脉导管(风险比,2.4;95%置信区间,1.1 - 5.8)。我们的研究结果有助于确定一组儿科患者,未来应针对这组患者进行干预以预防和治疗念珠菌血症。