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儿童侵袭性念珠菌病:儿童的流行病学与诊断

Pediatric Invasive Candidiasis: Epidemiology and Diagnosis in Children.

作者信息

Steinbach William J

机构信息

Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

出版信息

J Fungi (Basel). 2016 Jan 8;2(1):5. doi: 10.3390/jof2010005.

Abstract

Pediatric patients present with differing underlying conditions and cytotoxic therapeutic protocols, so the differing epidemiology of invasive candidiasis in children adults is not surprising. Understanding the species epidemiology is critical, as we often begin empiric therapy or therapy before antifungal susceptibilities are known. Reports with newer molecular diagnostic assays for invasive candidiasis are rare and require more study to develop firm pediatric-specific guidance. Antifungal treatment of pediatric candidiasis is reviewed in the context of larger epidemiologic studies and the few trials completed to date.

摘要

儿科患者存在不同的潜在疾病和细胞毒性治疗方案,因此儿童侵袭性念珠菌病的流行病学与成人不同并不奇怪。了解菌种流行病学至关重要,因为我们常常在了解抗真菌药敏情况之前就开始经验性治疗或治疗。关于侵袭性念珠菌病的新型分子诊断检测方法的报告很少,需要更多研究来制定明确的儿科特异性指南。本文结合更大规模的流行病学研究以及迄今为止完成的少数试验,对儿科念珠菌病的抗真菌治疗进行综述。

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本文引用的文献

1
Failure to Validate a Multivariable Clinical Prediction Model to Identify Pediatric Intensive Care Unit Patients at High Risk for Candidemia.
J Pediatric Infect Dis Soc. 2016 Dec;5(4):458-461. doi: 10.1093/jpids/piv024. Epub 2015 Apr 29.
3
False-positive (1,3) β-D-glucan assay in a patient with intracranial germinoma.
Pediatr Infect Dis J. 2015 Jun;34(6):676-7. doi: 10.1097/INF.0000000000000690.
4
Persistence of high-level (1,3)-β-D-glucan after candidemia following autologous peripheral SCT in a pediatric patient.
Bone Marrow Transplant. 2015 Jan;50(1):137-8. doi: 10.1038/bmt.2014.206. Epub 2014 Sep 22.
6
Pediatric Risk Factors for Candidemia Secondary to Candida glabrata and Candida krusei Species.
J Pediatric Infect Dis Soc. 2013 Sep;2(3):263-6. doi: 10.1093/jpids/pis093. Epub 2012 Oct 30.
7
Active surveillance of candidemia in children from Latin America: a key requirement for improving disease outcome.
Pediatr Infect Dis J. 2014 Feb;33(2):e40-4. doi: 10.1097/INF.0000000000000039.
8
Comparison of (1->3)-β-D-glucan, mannan/anti-mannan antibodies, and Cand-Tec Candida antigen as serum biomarkers for candidemia.
J Clin Microbiol. 2013 Apr;51(4):1158-64. doi: 10.1128/JCM.02473-12. Epub 2013 Jan 30.

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