Steinbach William J
Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
J Fungi (Basel). 2016 Jan 8;2(1):5. doi: 10.3390/jof2010005.
Pediatric patients present with differing underlying conditions and cytotoxic therapeutic protocols, so the differing epidemiology of invasive candidiasis in children adults is not surprising. Understanding the species epidemiology is critical, as we often begin empiric therapy or therapy before antifungal susceptibilities are known. Reports with newer molecular diagnostic assays for invasive candidiasis are rare and require more study to develop firm pediatric-specific guidance. Antifungal treatment of pediatric candidiasis is reviewed in the context of larger epidemiologic studies and the few trials completed to date.
儿科患者存在不同的潜在疾病和细胞毒性治疗方案，因此儿童侵袭性念珠菌病的流行病学与成人不同并不奇怪。了解菌种流行病学至关重要，因为我们常常在了解抗真菌药敏情况之前就开始经验性治疗或治疗。关于侵袭性念珠菌病的新型分子诊断检测方法的报告很少，需要更多研究来制定明确的儿科特异性指南。本文结合更大规模的流行病学研究以及迄今为止完成的少数试验，对儿科念珠菌病的抗真菌治疗进行综述。
