Giblin L, Hollander M, Little D, Hickey D, Donohoe J, Walshe J J, Dorman A, O'Kelly P, Conlon P J
Irish Renal Transplant Registry, Department of Nephrology, Beaumont Hospital, Beaumont Road, Dublin 9.
Ir J Med Sci. 2005 Apr-Jun;174(2):9-13. doi: 10.1007/BF03169122.
The aim of this paper was to evaluate patient and kidney graft survival rates in renal transplant recipients and compare the outcomes between the different patient age groups.
A retrospective review of all adult renal transplants performed at Beaumont Hospital between the years 1986-2001 was carried out. Patients were defined as 'elderly' if they were 65 years of age or older and 'younger' if less than 65 years at the time of transplantation. Patient and transplant graft survival rates were analysed for each age group.
Data were analysed on 1462 'younger' patients and 105 'elderly' renal transplant recipients. Estimated patient survival at 1, 5 and 10 years were 96%, 87% and 74% in the younger patient group compared to 85%, 59% and 33% in the elderly group. The adjusted graft survival rates (adjusted for death due to other causes and with a functioning graft in situ) for the younger group were 89%, 77% and 64% at one, five and ten years respectively, while for the elderly group, adjusted one, five and ten year survival rates were 89%, 83% and 70% respectively.
Although the elderly have a shorter life expectancy than the younger population they do benefit from renal transplantation similar to the younger recipients.
本文旨在评估肾移植受者的患者及肾移植存活率，并比较不同年龄组患者的治疗结果。
对1986年至2001年间在博蒙特医院进行的所有成人肾移植手术进行回顾性研究。患者年龄在65岁及以上者被定义为“老年”患者，移植时年龄小于65岁者为“年轻”患者。分析每个年龄组的患者及移植肾存活率。
对1462例“年轻”患者和105例“老年”肾移植受者的数据进行了分析。年轻患者组1年、5年和10年的预计患者存活率分别为96%、87%和74%，而老年患者组分别为85%、59%和33%。年轻组调整后的移植肾存活率（针对其他原因导致的死亡进行调整且移植肾原位功能良好）在1年、5年和10年时分别为89%、77%和64%，而老年组调整后的1年、5年和10年存活率分别为89%、83%和70%。
尽管老年人的预期寿命比年轻人短，但他们与年轻受者一样能从肾移植中获益。
