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粗糙脉孢菌中重复DNA的转录

Transcription of repetitive DNA in Neurospora crassa.

作者信息

Dutta S K, Chaudhuri R K

机构信息

Department of Botany, Howard University, Washington, DC 20059, USA.

出版信息

Mol Gen Genet. 1975;136(3):227-32. doi: 10.1007/BF00334017.

Abstract

Repeated DNA sequences of Neurospora crassa were isolated and characterized. Approximately 10-12% of N. crassa DNA sequence were repeated, of which 7.3% were found to be transcribed in mid-log phase of mycelial growth as measured by DNA:RNA hybridization. It is suggested that part of repetitive DNA transcripts in N. crassa were mitochondrial and part were nuclear DNA. Most of the nuclear repeated DNAs, however, code for rRNA and tRNA in N. crassa.

摘要

粗糙脉孢菌的重复DNA序列被分离并进行了表征。粗糙脉孢菌约10%-12%的DNA序列是重复的,通过DNA:RNA杂交测量发现,其中7.3%在菌丝体生长的对数中期被转录。有人提出,粗糙脉孢菌中部分重复DNA转录本是线粒体的,部分是核DNA的。然而,粗糙脉孢菌中大多数核重复DNA编码rRNA和tRNA。

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Nucleic Acids Res. 1974 Nov;1(11):1411-9. doi: 10.1093/nar/1.11.1411.
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Gene regulation for higher cells: a theory.高等细胞的基因调控:一种理论
Science. 1969 Jul 25;165(3891):349-57. doi: 10.1126/science.165.3891.349.
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Transcription of nonrepeated DNA in neonatal and fetal mice.新生和胎儿小鼠中非重复DNA的转录
Proc Natl Acad Sci U S A. 1971 Jan;68(1):172-6. doi: 10.1073/pnas.68.1.172.
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On the role of RNA in gene amplification.论RNA在基因扩增中的作用。
Proc Natl Acad Sci U S A. 1972 Jul;69(7):1746-8. doi: 10.1073/pnas.69.7.1746.

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