Gelderman A H, Rake A V, Britten R J
Proc Natl Acad Sci U S A. 1971 Jan;68(1):172-6. doi: 10.1073/pnas.68.1.172.
The transcription of nonrepeated DNA sequences was measured by hybridization of RNA from neonatal and fetal mice to mouse DNA using three different techniques. The measurements indicate that a large part (about 70%) of the rapidly-labeled fetal RNA is transcribed from nonrepeated DNA sequences. It appears that more than 12% of the single-copy DNA sequences are represented in the RNA of newborn mice.
使用三种不同技术,通过将新生小鼠和胎鼠的RNA与小鼠DNA杂交来测量非重复DNA序列的转录情况。测量结果表明,快速标记的胎鼠RNA中很大一部分(约70%)是由非重复DNA序列转录而来的。新生小鼠RNA中似乎有超过12%的单拷贝DNA序列得以体现。