Uslenghi S, Liversidge H M, Wong F S L
Dental Institute, Barts and The London School of Medicine and Dentistry, Turner Street, Whitechapel, London E1 2AD, UK.
Arch Oral Biol. 2006 Feb;51(2):129-33. doi: 10.1016/j.archoralbio.2005.06.004. Epub 2005 Aug 10.
To investigate the radiographic development of permanent teeth in a group of children (66 females and 69 males, aged 3.08-15.02 years) with agenesis of one or more permanent teeth compared to a matched group.
Tooth formation of all developing permanent teeth was assessed using Haavikko's method (1970) from dental panoramic tomographs. The difference between dental and chronological age was tested using a paired t-test. The correlation between the difference of dental and chronological age and severity of hypodontia was investigated using Spearman correlation test. In addition, radiographs of all children with only one single missing tooth in one quadrant and no more than two agenesis in total (N=59), were analyzed using the non-parametric Wilcoxon sign test, in order to investigate if the development of the teeth adjacent to the site of the agenesis was effected.
Tooth formation in children with hypodontia was significantly delayed compared to the matched group (p<0.001). The mean difference was 1.51 years (S.D. 1.37 years). The severity of the hypodontia effected the magnitude of the delay (p<0.01). The teeth adjacent to the site of the agenesis were significantly delayed compared to the corresponding teeth in the matched group (p<0.01).
These results confirm that the development of permanent teeth in children with hypodontia is different when compared with a matched group.
调查一组恒牙先天缺失（一颗或多颗恒牙）的儿童（66名女性和69名男性，年龄3.08 - 15.02岁）与匹配组相比恒牙的影像学发育情况。
使用哈维科方法（1970年），从牙科全景断层扫描评估所有正在发育恒牙的牙齿形成情况。使用配对t检验测试牙齿年龄与实际年龄之间的差异。使用斯皮尔曼相关性检验研究牙齿年龄与实际年龄的差异与牙列缺损严重程度之间的相关性。此外，对所有在一个象限中仅有一颗单颗缺失牙且总共不超过两颗恒牙先天缺失的儿童（N = 59）的X光片，使用非参数威尔科克森符号检验进行分析，以调查先天缺失部位相邻牙齿的发育是否受到影响。
与匹配组相比，牙列缺损儿童的牙齿形成明显延迟（p < 0.001）。平均差异为1.51岁（标准差1.37岁）。牙列缺损的严重程度影响延迟程度（p < 0.01）。与匹配组中相应牙齿相比，先天缺失部位相邻的牙齿明显延迟（p < 0.01）。
这些结果证实，与匹配组相比，牙列缺损儿童恒牙的发育有所不同。
