Oga M, Arizono T, Sugioka Y
Department of Orthopedics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Acta Orthop Scand. 1992 Jun;63(3):301-4. doi: 10.3109/17453679209154787.
We investigated the effect of tobramycin-impregnated polymethylmethacrylate (PMMA) bone cement on the adhesion and colonization of Staphylococcus epidermidis. The pattern of colonization was quantitated using plate count techniques and electron microscopy. Colonization of the tobramycin-impregnated disc surface by adhesive bacteria was demonstrated but it was less than in the control disc. This finding suggests that tobramycin may reduce bacterial adherence and proliferation on the PMMA surface.
我们研究了妥布霉素浸渍的聚甲基丙烯酸甲酯（PMMA）骨水泥对表皮葡萄球菌黏附和定植的影响。使用平板计数技术和电子显微镜对定植模式进行了定量分析。结果表明，黏附性细菌在妥布霉素浸渍的圆盘表面有定植，但比对照圆盘少。这一发现表明，妥布霉素可能会减少细菌在PMMA表面的黏附和增殖。
