Wellmer Frank, Riechmann José Luis
Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.
Int J Dev Biol. 2005;49(5-6):745-59. doi: 10.1387/ijdb.051991fw.
The analysis of the gene regulatory networks underlying development is of central importance for a better understanding of the mechanisms that control the formation of the different cell-types, tissues or organs of an organism. The recent invention of genomic technologies has opened the possibility of studying these networks at a global level. In this paper, we summarize some of the recent advances that have been made in the understanding of plant development by the application of genomic technologies. We focus on a few specific processes, namely flower and root development and the control of the cell cycle, but we also highlight landmark studies in other areas that opened new avenues of experimentation or analysis. We describe the methods and the strategies that are currently used for the analysis of plant development by genomic technologies, as well as some of the problems and limitations that hamper their application. Since many genomic technologies and concepts were first developed and tested in organisms other than plants, we make reference to work in non-plant species and compare the current state of network analysis in plants to that in other multicellular organisms.
分析发育过程中潜在的基因调控网络对于更好地理解控制生物体不同细胞类型、组织或器官形成的机制至关重要。基因组技术的最新发明为在全球范围内研究这些网络提供了可能性。在本文中，我们总结了通过应用基因组技术在理解植物发育方面取得的一些最新进展。我们重点关注几个特定过程，即花和根的发育以及细胞周期的控制，但我们也突出了其他领域的标志性研究，这些研究开辟了新的实验或分析途径。我们描述了目前用于通过基因组技术分析植物发育的方法和策略，以及一些阻碍其应用的问题和局限性。由于许多基因组技术和概念最初是在植物以外的生物体中开发和测试的，我们参考了非植物物种的研究工作，并将植物网络分析的现状与其他多细胞生物体的进行了比较。
