Ajay J Y, Gajula Pradeep Kumar, Kalaimagal K, Hari B N Vedha
Department of Pharmaceutical Technology, School of Chemical and Biotechnology, Shanmugha Arts, Science, Technology & Research Academy University, Tanjavur, Tamil Nadu, India.
Pharmacogn Rev. 2012 Jan;6(11):6-15. doi: 10.4103/0973-7847.95852.
This study aims to review the concept of biological rhythms in medicinal plants. Dictionariesgenerally define pharmacognosy as the subject of the study of crude drugs of plant and animal origin. The name is derived from the Greek words pharmakon (drug) and gnosis (knowledge). Today pharmacognosy is also defined as the study of physical, chemical, biochemical and biological properties of drugs, drug substances, or potential drugs or drug substances of natural origin, as well as the search for new drugs from natural sources. Also, another important phenomenon to be taken care of in the production of therapeutic compounds in medicinal plants is the use of circardian clock. The circardian clock is studied by chronobiology, which can be defined as a field of science that examines periodic (cyclic) phenomena in living organisms and their adaptation to solar and lunar related rhythms. Thus, it is the scientific study of the effect of time on living systems and of biological rhythms. Also rhythmic oscillations in plants lead to the enormous production of particular compounds in plants at particular time, which may or may not produce any therapeutic effect in humans. Thus, the study of chronobiology and pharmacognosy can be put together as chronopharmacognosy.
本研究旨在综述药用植物中的生物节律概念。字典通常将生药学定义为研究植物和动物来源的天然药物的学科。这个名字来源于希腊语pharmakon(药物)和gnosis(知识)。如今,生药学也被定义为研究药物、原料药或天然来源的潜在药物或原料药的物理、化学、生物化学和生物学特性,以及从天然来源寻找新药。此外,在药用植物中生产治疗性化合物时需要关注的另一个重要现象是昼夜节律钟的作用。昼夜节律钟是由时间生物学研究的,时间生物学可定义为一门研究生物体中的周期性(循环性)现象及其对与太阳和月亮相关节律的适应性的科学领域。因此,它是对时间对生命系统的影响和生物节律的科学研究。植物中的节律性振荡也会导致植物在特定时间大量产生特定化合物,这些化合物可能对人类产生治疗作用,也可能不会。因此,时间生物学和生药学的研究可以整合为时间生药学。