急性巨细胞病毒感染并发静脉血栓形成：一例报告
Acute cytomegalovirus infection complicated by venous thrombosis: a case report.
作者信息
Rovery Clarisse, Granel Brigitte, Parola Philippe, Foucault Cédric, Brouqui Philippe
机构信息
Unité des Rickettsies, UMR6020, Faculté de Médecine, Université de la Méditerranée, Marseille, France.
出版信息
Ann Clin Microbiol Antimicrob. 2005 Aug 12;4:11. doi: 10.1186/1476-0711-4-11.
Abstract
BACKGROUND
CMV-induced vasculopathy and thrombosis have been reported, but they are rare conditions usually encountered in immunocompromised patients. However more and more complications of CMV infections are recognized in immunocompetent patients.
CASE PRESENTATION
We present a case report of a previously healthy adult with cytomegalovirus infection that was complicated by tibiopopliteal deep venous thrombosis and in whom Factor V Leiden heterozygous mutation was found.
CONCLUSION
This new case report emphasizes the involvement of cytomegalovirus in induction of vascular thrombosis in patients with predisposing risk factors for thrombosis. It is necessary to screen for CMV infection in patients with spontaneous thrombosis and an history of fever.
摘要
背景
巨细胞病毒（CMV）诱导的血管病变和血栓形成已有报道，但它们是免疫功能低下患者中常见的罕见病症。然而，免疫功能正常的患者中越来越多的CMV感染并发症被识别出来。
病例报告
我们报告一例既往健康的成年人感染巨细胞病毒，并发胫腘静脉深静脉血栓形成，且发现其存在因子V莱顿杂合突变。
结论
这一新的病例报告强调了巨细胞病毒在具有血栓形成易感危险因素的患者中诱导血管血栓形成的作用。对于有自发血栓形成且有发热病史的患者，筛查CMV感染是必要的。
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