Sandercock Gavin R H, Bromley Paul D, Brodie David A
Research Centre for Health Studies, Buckinghamshire Chilterns University College, Newlands Park, Gorelands Lane, Chalfont St.Giles, Buckinghamshire HP8 4AD, United Kingdom.
Int J Cardiol. 2005 Sep 1;103(3):238-47. doi: 10.1016/j.ijcard.2004.09.013.
Short-term assessment of heart rate variability (HRV) is a non-invasive technique to examine ANS function. Within the literature, HRV is commonly referred to as a reliable measurement technique. The aim of this review was to assess the accuracy of this description based upon a comprehensive review of the available data concerning reliability of short-term HRV measures. Reviewing only studies using appropriate statistical analyses, it was determined that reliability coefficients for HRV measures were highly varied. Coefficients of variation ranged from <1% to >100%. Similar variation was found in studies using the intraclass correlation coefficient values, and limits of agreement. Reliability coefficients reported displayed some distinct patterns. Firstly, where measurements were made during interventions such as tilt or pharmacological stimulation, reliability was poorer than when HRV was measured at rest. Secondly, clinical populations displayed poorer reliability than healthy subjects. There was little effect of test-retest duration on reliability and although no single HRV measurement appeared less reliable than another, there was evidence that optimal data collection conditions for specific frequency domain measures exist. Describing HRV as a reliable measurement technique appears to be a gross oversimplification, as results of reliability studies are heterogeneous, and dependent on a number of factors. Further studies are required, particularly in clinical populations to assess HRV reliability. Authors should refer to coefficients from similar populations measured under similar conditions when making future sample size calculations.
心率变异性（HRV）的短期评估是一种用于检查自主神经系统（ANS）功能的非侵入性技术。在文献中，HRV通常被认为是一种可靠的测量技术。本综述的目的是基于对有关短期HRV测量可靠性的现有数据的全面回顾，评估这一描述的准确性。仅回顾使用适当统计分析的研究后发现，HRV测量的可靠性系数差异很大。变异系数范围从<1%到>100%。在使用组内相关系数值和一致性界限的研究中也发现了类似的差异。报告的可靠性系数呈现出一些明显的模式。首先，在诸如倾斜或药物刺激等干预过程中进行测量时，可靠性比在静息状态下测量HRV时要差。其次，临床人群的可靠性比健康受试者差。重测持续时间对可靠性影响不大，虽然没有单一的HRV测量似乎比其他测量更不可靠，但有证据表明特定频域测量存在最佳数据收集条件。将HRV描述为一种可靠的测量技术似乎是一种过于简单的概括，因为可靠性研究的结果是异质性的，并且取决于许多因素。需要进一步的研究，特别是在临床人群中评估HRV的可靠性。作者在进行未来样本量计算时，应参考在类似条件下测量的类似人群的系数。
