Sieben Judith M, Vlaeyen Johan W S, Portegijs Piet J M, Verbunt Jeanine A, van Riet-Rutgers Sita, Kester Arnold D M, Von Korff Michael, Arntz Arnoud, Knottnerus J André
Department of General Practice, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands.
Pain. 2005 Sep;117(1-2):162-70. doi: 10.1016/j.pain.2005.06.002.
Recently, fear-avoidance models have been quite influential in understanding the transition from acute to chronic low back pain (LBP). Not only has pain-related fear been found to be associated with disability and increased pain severity, but also treatment focused at reducing pain-related fear has shown to successfully reduce disability levels. In spite of these developments, there is still a lack in well-designed prospective studies examining the role of pain-related fear in acute back pain. The aim of the current study was to prospectively test the assumption that pain-related fear in acute stages successfully predicts future disability. Subjects were primary care acute LBP patients consulting because of a new episode of LBP (<or=3 weeks). They completed questionnaires on background variables, fear-avoidance model variables and LBP outcome (Graded Chronic Pain Scale, GCPS) at baseline, 3, 6, and 12 months follow-up and at the end of the study. Two-hundred and twenty-two acute LBP patients were included, of whom 174 provided full follow-up information (78.4%). A backward ordinal regression analysis showed previous LBP history and pain intensity to be the most important predictors of end of study GCPS. Of the fear-avoidance model variables, only negative affect added to this model. Our results do not really support the longitudinal validity of the fear-avoidance model, but they do feed the discussion on the role of pain-related fear in early stages of LBP.
最近,恐惧回避模型在理解从急性下背痛(LBP)向慢性下背痛的转变过程中颇具影响力。研究发现,不仅与疼痛相关的恐惧与残疾及疼痛严重程度增加有关,而且专注于减轻与疼痛相关恐惧的治疗已显示能成功降低残疾水平。尽管有这些进展,但仍缺乏精心设计的前瞻性研究来检验与疼痛相关的恐惧在急性背痛中的作用。本研究的目的是前瞻性地检验急性阶段与疼痛相关的恐惧能否成功预测未来残疾这一假设。研究对象为因新发下背痛(≤3周)前来咨询的初级保健急性下背痛患者。他们在基线、3个月、6个月、12个月随访以及研究结束时完成了关于背景变量、恐惧回避模型变量和下背痛结局(分级慢性疼痛量表,GCPS)的问卷调查。共纳入222例急性下背痛患者,其中174例提供了完整的随访信息(78.4%)。向后有序回归分析表明,既往下背痛病史和疼痛强度是研究结束时GCPS的最重要预测因素。在恐惧回避模型变量中,只有消极情绪被纳入该模型。我们的结果并未真正支持恐惧回避模型的纵向有效性,但确实为有关与疼痛相关的恐惧在LBP早期阶段作用的讨论提供了依据。