Noyola Daniel E, Valdez-López Beatriz H, Hernández-Salinas Alba E, Santos-Díaz Miguel A, Noyola-Frías Miguel A, Reyes-Macías Juan F, Martínez-Martínez Leticia G
Departamento de Microbiología, Universidad Autónoma de San Luis Potosí, Mexico.
Arch Med Res. 2005 Sep-Oct;36(5):590-3. doi: 10.1016/j.arcmed.2005.03.045.
Healthy children attending day-care centers (DCC) may excrete cytomegalovirus (CMV) frequently. Mothers of children excreting CMV are at higher risk for acquiring this infection than mothers of children not excreting CMV. Despite the increased attendance to DCC by children there is a lack of information regarding CMV infection in Mexico.
Prospective determination of CMV excretion in saliva of children attending public and private DCC. Three saliva samples were collected during a 2-month follow-up period from participating children and the presence of CMV was determined by viral culture. Demographic features of children and DCC type were taken into account when comparing children with and without CMV excretion.
One hundred fifty-two children participated in the study (84 from public and 68 from private DCC). Overall, 17 (11.2%) children excreted CMV during the study period. Excretion rates varied between DCC from 3.1 to 31.3%. Children from private DCC were as likely to excrete CMV as children from public DCC. There were no demographic or clinical features of children associated with viral excretion.
CMV was excreted on an average of 11.2% children attending DCC. The type of DCC or other demographic features were not associated with the likelihood of CMV excretion. CMV seronegative mothers of children who attend DCC need to be aware of the possibility of CMV acquisition and transmission in DCC.
在日托中心（DCC）的健康儿童可能频繁排出巨细胞病毒（CMV）。排出CMV的儿童的母亲比未排出CMV的儿童的母亲感染这种病毒的风险更高。尽管儿童对日托中心的出勤率有所增加，但墨西哥缺乏有关CMV感染的信息。
前瞻性测定在公立和私立日托中心的儿童唾液中的CMV排出情况。在2个月的随访期内，从参与研究的儿童中收集三份唾液样本，并通过病毒培养确定CMV的存在。在比较排出和未排出CMV的儿童时，考虑了儿童的人口统计学特征和日托中心类型。
152名儿童参与了研究（84名来自公立日托中心，68名来自私立日托中心）。总体而言，17名（11.2%）儿童在研究期间排出了CMV。各日托中心的排出率在3.1%至31.3%之间。私立日托中心的儿童排出CMV的可能性与公立日托中心的儿童相同。儿童的人口统计学或临床特征与病毒排出无关。
在日托中心的儿童中，平均有11.2%排出CMV。日托中心的类型或其他人口统计学特征与CMV排出的可能性无关。在日托中心的儿童的CMV血清阴性母亲需要意识到在日托中心感染和传播CMV的可能性。
