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[新生儿髋关节发育不良的超声筛查及使用弗雷卡枕治疗]

[Ultrasound screening for hip dysplasia in newborns and treatment with Frejka pillow].

作者信息

Blom Hans Christian, Heldaas Ola, Manoharan Pat, Andersen Bjarne D, Søia Lise

出版信息

Tidsskr Nor Laegeforen. 2005 Aug 11;125(15):1998-2001.

Abstract

BACKGROUND

The prevailing strategy concerning ultrasound screening for DDH in newborns in Norway does not intercept all who should be treated. In recent years typical rates for hospital treatment of late hip dislocations in newborn have been 15-20 cases. By universal ultrasound examination, 10-20 % of the newborns present with "physiological immature" hips. By this we mean hips with subnormal ultrasound values that will normalise in the course of the neonatal period. An agreed basis of defined and standardised criteria in order to diagnose and treat physiological immature hips is required. We hope tat this study will contribute to the final solution to these questions.

MATERIAL AND METHODS

Over the period 1 February 1998 through 2002 we had 2466 alive newborns at our hospital. 26 were directly transferred to another hospital, 130 were left out because of limited skills or inadequate training in ultrasound among temporary staff. The hips have been graduated morphologically in accordance with Graf's alpha angle. All newborns have been investigated by ultrasound and clinical examination with Ortolani/Barlow test 1-3 day after birth. Those with diagnosed dysplasia (alpha < 50 masculine) and those with positive clinic and physiological immature hip were immediately treated with Frejka pillow. Those with negative clinic and physiological immature hip were revaluated after 4 weeks by ultrasound, and those still immature were given Frejka pillow. Duration of pillow treatment was 4 months, followed by further clinically and radiological surveillance. All infants given the pillow treatment were clinically examined 2-3 months after they were able to walk without support, and again 1-5 years later radiologically.

RESULTS

Of the newborn, 31 (1.3%) had a positive Ortolani/Barlow test. Among them, 7 had dysplasia, 20 immature hip; 4 were normal. Among the 2275 infants with normal clinic, 9 had dysplasia and 232 (10.9%) had at least one physiological immature hip. After 4 weeks, 26 still had immature hip by ultrasound evaluation. A total of 62 infants (2.7%) were treated with Frejka pillow. At the "walk alone" control and the radiological control 1-5 years later, there were no pathological findings, specially no sign of aseptic necrosis. In the total material we had 2 girls with late subluxations, detected at the age of 8 and 10 months. Both had normal clinic with an ultrasound immature hip at birth. They should have been followed up, but were missed, for uncertain reasons. Both attained normal hips after treatment.

CONCLUSION

Our study of universal ultrasound screening for DDH of the hips in newborns shows that 1 % of the infants born with normal hips clinically still have physiological immature hips at the age of 4 weeks. Taking those into account as potentially dysplastic, it gives an overall treatment rate of 2.7%. Today, the only possible way to intercept those physiological immature hips that will not normalise is by universal ultrasound examination. For these children, early treatment with Frejka pillow is effective, without any risk of iatrogenic injury.

摘要

背景

挪威现行的新生儿发育性髋关节发育不良(DDH)超声筛查策略未能涵盖所有应接受治疗的病例。近年来,新生儿晚期髋关节脱位的医院治疗典型病例数为15 - 20例。通过普遍的超声检查,10% - 20%的新生儿存在“生理性未成熟”髋关节。我们所说的生理性未成熟髋关节是指超声值低于正常水平且在新生儿期会恢复正常的髋关节。需要一个商定的、明确且标准化的标准基础来诊断和治疗生理性未成熟髋关节。我们希望这项研究能为这些问题的最终解决做出贡献。

材料与方法

在1998年2月1日至2002年期间,我院有2466例存活新生儿。26例直接转至其他医院,130例因临时工作人员超声技能有限或培训不足而被排除。根据格拉夫(Graf)阿尔法角对髋关节进行形态学分级。所有新生儿在出生后1 - 3天接受超声检查和奥尔托拉尼(Ortolani)/巴洛(Barlow)试验临床检查。诊断为发育不良(阿尔法角<50°男性型)以及临床检查阳性且生理性未成熟髋关节的患儿立即使用弗雷卡(Frejka)枕进行治疗。临床检查阴性且生理性未成熟髋关节的患儿在4周后通过超声复查,仍未成熟的给予弗雷卡枕。枕疗持续4个月,之后进行进一步的临床和放射学监测。所有接受枕疗的婴儿在能够独立行走后2 - 3个月进行临床检查,并在1 - 5年后再次进行放射学检查。

结果

新生儿中,31例(1.3%)奥尔托拉尼/巴洛试验阳性。其中,7例发育不良,20例髋关节未成熟;4例正常。在2275例临床检查正常的婴儿中,9例发育不良,232例(10.9%)至少有一个生理性未成熟髋关节。4周后,超声评估仍有26例髋关节未成熟。共有62例婴儿(2.7%)接受了弗雷卡枕治疗。在“独立行走”检查以及1 - 5年后的放射学检查中,未发现病理改变,特别是没有无菌性坏死的迹象。在全部病例中,我们有2例女童出现晚期半脱位,分别在8个月和10个月时被发现。她们出生时临床检查正常且超声显示髋关节未成熟。她们本应接受随访,但因不明原因被遗漏。两人治疗后髋关节均恢复正常。

结论

我们对新生儿髋关节DDH进行普遍超声筛查的研究表明,临床髋关节正常的新生儿中,1%在4周龄时仍存在生理性未成熟髋关节。将这些病例视为潜在发育不良病例,总体治疗率为2.7%。如今,拦截那些不会恢复正常的生理性未成熟髋关节的唯一可行方法是进行普遍超声检查。对于这些儿童,早期使用弗雷卡枕治疗有效,且无任何医源性损伤风险。

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