Deshields Teresa, Tibbs Tiffany, Fan Ming-Yu, Taylor Marie
Alvin J. Siteman Cancer Center, 4921 Parkview Place, St. Louis, MO 63110, USA.
Psychooncology. 2006 May;15(5):398-406. doi: 10.1002/pon.962.
Depression is a significant problem for some breast cancer survivors after the end of treatment. This study assessed depression using the CES-D for 84 breast cancer patients at the conclusion of radiation treatment, and at 3 and 6 months post-treatment. Based on the pattern of CES-D scores, patients were divided into five groups: (1) Stay Depressed (scores above clinical cutoff for depression at all timepoints); (2) Recover (above threshold at baseline, but below at follow-up); (3) Become Depressed (below threshold at baseline, but above at follow-up); (4) Never Depressed (below threshold at all times); and (5) Vacillate (none of the above patterns). This study examined the relationships between depression groups and a variety of medical, demographic, and psychological measures, including anxiety and quality of life (QOL). Number of children at home significantly distinguished the groups, with the Become Depressed group having more children and the Vacillate group having fewer children. Anxiety levels were different among the groups, with Recover and Never Depressed groups having consistently lower anxiety scores. QOL scores also distinguished the groups in that Never Depressed patients demonstrated better QOL than all other groups. The findings have implications for understanding resilience in cancer patients.
对于一些乳腺癌幸存者来说，治疗结束后抑郁症是一个严重的问题。本研究在放疗结束时、治疗后3个月和6个月，使用流调中心抑郁量表（CES-D）对84名乳腺癌患者的抑郁情况进行了评估。根据CES-D评分模式，患者被分为五组：（1）持续抑郁（在所有时间点的得分均高于抑郁症临床临界值）；（2）康复（基线时高于临界值，但随访时低于临界值）；（3）变得抑郁（基线时低于临界值，但随访时高于临界值）；（4）从未抑郁（在所有时间均低于临界值）；（5）波动型（不属于上述任何一种模式）。本研究考察了抑郁分组与各种医学、人口统计学和心理指标之间的关系，包括焦虑和生活质量（QOL）。家中子女数量在各分组之间有显著差异，变得抑郁组的子女更多，波动型组的子女更少。各分组之间的焦虑水平也有所不同，康复组和从未抑郁组的焦虑得分一直较低。生活质量得分在各分组之间也有差异，从未抑郁的患者表现出比所有其他组更好的生活质量。这些发现对于理解癌症患者的恢复力具有启示意义。
