Baeza O R, Majid N K, Conroy D P, Donahoo J S
Eastern Heart Institute, General Hospital Center, Passaic, New Jersey.
Ann Thorac Surg. 1992 Jul;54(1):62-7. doi: 10.1016/0003-4975(92)91141-u.
Ultrasound decalcification of aortic valve stenosis was performed in 31 patients. There were 16 men and 15 women with a mean age of 71.03 +/- 9.6 years (range, 51 to 89 years). Each had severe calcific aortic stenosis with an aortic valve gradient greater than 40 mm Hg, aortic valve area (AVA) less than 0.6 cm2, and no serious insufficiency. Feasibility of aortic valve debridement was determined under direct vision. Intraoperative epicardial or transesophageal color Doppler two-dimensional echocardiography was used before and after the aortic valve debridement to evaluate aortic cusp motion and aortic regurgitation. Direct transseptal aortic valve gradient was measured on all patients before and after aortic valve debridement, and the AVA was determined. Aortic valve debridement was performed as the primary procedure in 17 cases and combined with other cardiac procedures in 14 patients. Preoperative aortic valve gradient was reduced from 72.5 +/- 22.5 mm Hg (range, 40 to 130 mm Hg) to 15.5 +/- 11.9 mm Hg (range, 2 to 50 mm Hg), and the average AVA of 0.41 +/- 0.10 cm2 (range, 0.22 to 0.63 cm2) was increased to 1.55 +/- 0.58 cm2 (range, 0.65 to 3.50 cm2) after ultrasound decalcification. There were two early deaths in octogenerian, high-risk patients, and two late deaths (6.45% early and 6.45% late mortality), none of them related to AVD. Postoperative follow-up included clinical evaluation and color Doppler echocardiography every 6 months. The aortic valve gradient was measured using a continuous-wave Doppler probe, and the AVA was calculated by the simplified continuity equation: AVA = aAOA x vLVOT/vAV.(ABSTRACT TRUNCATED AT 250 WORDS)
对31例主动脉瓣狭窄患者实施了超声钙化消融术。其中男性16例,女性15例,平均年龄71.03±9.6岁(范围51至89岁)。每位患者均患有严重钙化性主动脉瓣狭窄,主动脉瓣压差大于40 mmHg,主动脉瓣面积(AVA)小于0.6 cm²,且无严重关闭不全。在直视下确定主动脉瓣清创的可行性。在主动脉瓣清创前后使用术中的心外膜或经食管彩色多普勒二维超声心动图评估主动脉瓣叶运动和主动脉瓣反流。在所有患者的主动脉瓣清创前后测量直接经中隔主动脉瓣压差,并确定AVA。17例患者将主动脉瓣清创作为主要手术,14例患者与其他心脏手术联合进行。术前主动脉瓣压差从72.5±22.5 mmHg(范围40至130 mmHg)降至15.5±11.9 mmHg(范围2至50 mmHg),超声钙化消融术后平均AVA从0.41±0.10 cm²(范围0.22至0.63 cm²)增加到1.55±0.58 cm²(范围0.65至3.50 cm²)。80岁以上的高危患者中有2例早期死亡,2例晚期死亡(早期死亡率6.45%,晚期死亡率6.45%),均与主动脉瓣清创无关。术后随访包括每6个月进行一次临床评估和彩色多普勒超声心动图检查。使用连续波多普勒探头测量主动脉瓣压差,并通过简化连续性方程计算AVA:AVA = aAOA×vLVOT/vAV。(摘要截断于250字)