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主动脉瓣钙化狭窄的磨除清创术。近期及中期临床结果。

Abrasion-debridement of aortic valve calcific stenosis. Immediate and mid-term clinical results.

作者信息

Mezzacapo B

机构信息

Institute Multichair of Thoracic and Cardiovascular Surgery, University of Siena, Italy.

出版信息

J Cardiovasc Surg (Torino). 1998 Oct;39(5):667-72.

PMID:9833731
Abstract

BACKGROUND

Ultrasonic debridement of aortic valve calcific stenosis has been abandoned because of high incidence of late insufficiency, due to retraction of cusps damaged by ultrasonic energy. The feasibility of alternative decalcification technique has been tested at the Department of Thoracic and Cardiovascular Surgery of the University of Siena, Italy, using the abrasive power of a diamond burr, actioned by electrical high speed motor.

METHODS

Between January 1995 and March 1996, fifteen patients underwent aortic decalcification. Mean age was 69.6 years.

RESULTS

All were symptomatic and 46% had associated coronary or mitral valve disease. Mean preoperative peak systolic echo-cardiographic gradient was 76+/-24.2 mmHs and valve area 0.87+/-0.31 at echoplanimetry. No moderate to severe aortic insufficiency was allowed. Valve debridement was achieved without mortality and morbidity procedure-related. Transvalvular hemodynamic gradient disappeared in 8 patients and fell in 7 from a mean value of 81.5 to 29.7 mmHg. The valvular area increased to a mean value of 2.4 cm2. At mid-term follow-up (mean 16.9 months, range 12 to 25) all patients remained clinically improved and free of complications. No case of new aortic incontinence nor worsening has been observed at echocardiographic control. The valve area was calculated 1.54+/-0.47 by continuity equation.

CONCLUSIONS

Although these results are encouraging, more experience and longer follow-up are necessary, before giving affordable guide-lines regarding the indication for abrasion-debridement technique in a clinical setting.

摘要

背景

由于超声能量损伤瓣叶回缩导致晚期关闭不全发生率高,主动脉瓣钙化狭窄的超声清创术已被摒弃。意大利锡耶纳大学胸心血管外科使用电动高速马达驱动的金刚石磨头的研磨力,测试了替代脱钙技术的可行性。

方法

1995年1月至1996年3月,15例患者接受了主动脉脱钙。平均年龄为69.6岁。

结果

所有患者均有症状,46%伴有冠状动脉或二尖瓣疾病。术前超声心动图收缩期峰值平均梯度为76±24.2 mmHg,平面测量时瓣膜面积为0.87±0.31。不允许出现中度至重度主动脉瓣关闭不全。瓣膜清创术无手术相关死亡率和发病率。8例患者跨瓣膜血流动力学梯度消失,7例患者从平均81.5 mmHg降至29.7 mmHg。瓣膜面积增加至平均2.4 cm²。中期随访(平均16.9个月,范围12至25个月)时,所有患者临床症状均改善且无并发症。超声心动图检查未观察到新的主动脉瓣反流病例或病情恶化。通过连续方程计算瓣膜面积为1.54±0.47。

结论

尽管这些结果令人鼓舞,但在给出关于临床环境中磨蚀清创技术适应证的实用指南之前,还需要更多经验和更长时间的随访。

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