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超声手术吸引器行主动脉瓣清创术:需谨慎行事。

Aortic valve debridement by ultrasonic surgical aspirator: a word of caution.

作者信息

Craver J M

机构信息

Division of Cardio-Thoracic Surgery, Joseph B. Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, Georgia.

出版信息

Ann Thorac Surg. 1990 May;49(5):746-52; discussion 752-3. doi: 10.1016/0003-4975(90)90014-w.

Abstract

Aortic stenosis was relieved in 11 patients by ultrasonic debridement of the valve and annulus, while 102 other patients underwent valve replacement for aortic stenosis during 1988. Debridement was selectively applied based on findings of small annulus size (19 mm or less) and extensive calcification. Additional patient characteristics were mean transvalvular gradient of 78 mm Hg, advanced age, and marked left ventricular hypertrophy. Six patients had no residual gradient and 5 others a mean gradient less than 10 mm Hg. There were no complications related to the debridement process. Intraoperative transesophageal Doppler echocardiography demonstrated improved leaflet mobility and elimination of the gradient in all patients and elimination of associated valvular insufficiency in 2 patients. Follow-up echocardiography demonstrated late onset of new valvular regurgitation in 5 patients that was progressive and required reoperation in 3. Thickened, hardened, and retracted valve leaflets with loss of central coaptation were found in all 3 patients who underwent reoperation. Ultrasonic debridement can effectively relieve aortic stenosis, provide an excellent immediate hemodynamic result, and decrease operative time. However, the early occurrence of aortic insufficiency in a high percentage of patients makes it an unacceptable alternative to valve replacement, and the technique should be abandoned as a treatment for severe calcific aortic stenosis.

摘要

1988年,11例患者通过对瓣膜及瓣环进行超声清创术缓解了主动脉瓣狭窄,另有102例患者因主动脉瓣狭窄接受了瓣膜置换术。清创术是根据瓣环尺寸小(19毫米或更小)及广泛钙化的情况选择性应用的。其他患者特征包括平均跨瓣压差78毫米汞柱、高龄以及明显的左心室肥厚。6例患者无残余压差,另外5例平均压差小于10毫米汞柱。未出现与清创过程相关的并发症。术中经食管多普勒超声心动图显示,所有患者的瓣叶活动改善且压差消除,2例患者的相关瓣膜关闭不全消除。随访超声心动图显示,5例患者出现新的瓣膜反流,呈进行性发展,其中3例需要再次手术。接受再次手术的所有3例患者均发现瓣膜增厚、硬化、回缩,中央对合消失。超声清创术可有效缓解主动脉瓣狭窄,立即产生良好的血流动力学效果并缩短手术时间。然而,高比例患者早期出现主动脉瓣关闭不全,使其成为瓣膜置换术不可接受的替代方法,该技术应不再作为重度钙化性主动脉瓣狭窄的治疗方法。

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