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心内膜心肌纤维化患者的二尖瓣修复术。

Mitral valve repair in patients with endomyocardial fibrosis.

作者信息

Uva M S, Jebara V A, Acar C, Dervanian P, Chauvaud S, Fuzellier J F, Fabiani J N, Deloche A, Carpentier A F

机构信息

Department of Cardiovascular Surgery, Hôpital Broussais, Paris, France.

出版信息

Ann Thorac Surg. 1992 Jul;54(1):89-92. doi: 10.1016/0003-4975(92)91146-z.

Abstract

Between 1987 and 1990, 12 patients were operated on for endomyocardial fibrosis at our institution. Nine were treated by endocardectomy and mitral valve repair and constitute the material of this study. Ages ranged from 9 to 58 years (mean age, 32.5 years). Biventricular involvement was present in 3 cases, and 6 patients had predominantly left ventricular endomyocardial fibrosis. Six patients were in New York Heart Association class III/IV. Six patients had severe mitral insufficiency (3 to 4/4) and 3 patients had moderate mitral insufficiency (2/4). The operation consisted of left ventricular endocardectomy with complete detachment and mobilization of the posterior leaflet of the mitral valve in all cases. An autologous pericardial patch was used to reconstruct posterior leaflet continuity in 4 patients. In 7 patients a prosthetic mitral ring was used. In 3 patients right ventricular endocardectomy and tricuspid valve repair were also performed. All patients survived and none required early reoperation. Follow-up was complete and ranged from 9 to 38 months. No late deaths occurred, and 1 patient required mitral valve replacement for recurrent mitral regurgitation. Doppler echocardiographic studies were performed in 7 patients and revealed no or mild mitral insufficiency. In conclusion, mitral valve repair is safe and offers good early and late results in patients with endomyocardial fibrosis.

摘要

1987年至1990年间,我院有12例患者接受了心内膜心肌纤维化手术治疗。其中9例接受了心内膜切除术和二尖瓣修复术,构成了本研究的材料。年龄范围为9至58岁(平均年龄32.5岁)。3例患者双心室受累,6例患者主要为左心室心内膜纤维化。6例患者属于纽约心脏协会III/IV级。6例患者有严重二尖瓣关闭不全(3至4/4级),3例患者有中度二尖瓣关闭不全(2/4级)。所有病例的手术均包括左心室心内膜切除术,并完全游离和活动二尖瓣后叶。4例患者使用自体心包补片重建后叶连续性。7例患者使用了人工二尖瓣环。3例患者还进行了右心室心内膜切除术和三尖瓣修复术。所有患者均存活,无一例需要早期再次手术。随访完整,时间为9至38个月。无晚期死亡病例,1例患者因复发性二尖瓣反流需要进行二尖瓣置换术。7例患者进行了多普勒超声心动图检查,结果显示无或仅有轻度二尖瓣关闭不全。总之,二尖瓣修复术对心内膜心肌纤维化患者来说是安全的,并且能带来良好的早期和晚期效果。

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