Russo P A, Wright J E, Ho S Y, Maneksa J R, Clitsakis D
Thorax. 1985 Aug;40(8):621-5. doi: 10.1136/thx.40.8.621.
Two patients with endomyocardial fibrosis of the left ventricle were treated by endocardectomy plus mitral valve replacement. In both cases the results of surgery were satisfactory. No consequences related to eosinophilia, which was present before operation in one of them, were noted. The poor prognosis of this progressive disease and the inefficiency of medical treatment compared with the good surgical results already reported from various centres encourage early operation for all patients with endomyocardial fibrosis who have symptoms. Because of the pathophysiology of the disease, endocardectomy should be attempted in all cases and anti-coagulant treatment continued for life.
两名左心室心内膜纤维化患者接受了心内膜切除术加二尖瓣置换术治疗。两例手术结果均令人满意。其中一例术前存在嗜酸性粒细胞增多症,但未发现与之相关的后果。这种进行性疾病预后较差,药物治疗效果不佳,而各中心已报道的良好手术结果表明,对于所有有症状的心内膜纤维化患者应尽早手术。由于该疾病的病理生理学特点,所有病例均应尝试心内膜切除术,并终身持续抗凝治疗。